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Article
Open AccessA multi-channel stimulator with an active electrode array implant for vagal-cardiac neuromodulation studies
Implantable vagus nerve stimulation is a promising approach for restoring autonomic cardiovascular functions after heart transplantation. For successful treatment a system should have multiple electrodes to de...
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Article
Open AccessHierarchical graph learning with convolutional network for brain disease prediction
In computer-aided diagnostic systems, the functional connectome approach has become a common method for detecting neurological disorders. However, the existing methods either ignore the uniqueness of different...
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Article
Open AccessDental pulp stem cell-derived exosomes revitalize salivary gland epithelial cell function in NOD mice via the GPER-mediated cAMP/PKA/CREB signaling pathway
Restoration of salivary gland function in Sjogren’s syndrome (SS) is still a challenge. Dental pulp stem cells (DPSCs) derived exosomes had shown anti-inflammatory, anti-oxidative, immunomodulatory, and tissue...
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Article
Why does batch normalization induce the model vulnerability on adversarial images?
Batch normalization is one of the most widely used components in deep neural networks. It can accelerate training, and boost model performance on normal samples. However, batch normalization induces vulnerabil...
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Chapter and Conference Paper
Autonomous UAV Gas Pollution Source Locating Method Based on Concentration Diffusion Gradient
Gas pollution control is an urgent issue in develo** countries, which has become a global concern. In this paper, considering the deficiencies in the illegal gas emission supervisory system, and the difficul...
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Article
Open AccessThe pattern and treatment outcomes for rectal cancer with concurrent locoregional recurrence and distant metastases after total mesorectal excision
To study the pattern and treatment outcome of rectal cancer (RC) with concurrent locoregional recurrence (LR) and distant metastasis (DM) after total mesorectal excision (TME) and to identify patient-, disease...
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Article
High efficiency giant magnetoresistive device based on two-dimensional MXene (Mn2NO2)
Due to the unique electronic structure of half-metals, characterized by the conductivity of majority-spin and the band gap of minority-spin, these materials have emerged as suitable alternatives for the design...
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Article
Open AccessLetter to the Editor: An ultra-sensitive assay using cell-free DNA fragmentomics for multi-cancer early detection
Early detection can benefit cancer patients with more effective treatments and better prognosis, but existing early screening tests are limited, especially for multi-cancer detection. This study investigated t...
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Article
Open AccessMulti-dimensional fragmentomic assay for ultrasensitive early detection of colorectal advanced adenoma and adenocarcinoma
Previous studies on liquid biopsy-based early detection of advanced colorectal adenoma (advCRA) or adenocarcinoma (CRC) were limited by low sensitivity. We performed a prospective study to establish an integra...
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Article
Multiparametric MRI-based radiomics signature for preoperative estimation of tumor-stroma ratio in rectal cancer
To determine whether a radiomics signature (rad-score) outperforms ADC in TSR estimation by develo** a radiomics biomarker for preoperative TSR diagnosis in rectal cancer.
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Article
Open AccessLaparoscopic surgery may decrease the risk of clinical anastomotic leakage and a nomogram to predict anastomotic leakage after anterior resection for rectal cancer
Anastomotic leakage is still one of the most dreaded complications after anterior resection for rectal cancer. This study aimed to identify risk factors for anastomotic leakage and to create a nomogram for pre...
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Article
Open AccessTemporary Diverting Stoma Improves Recovery of Anastomotic Leakage after Anterior Resection for Rectal Cancer
Temporary diverting stoma might be a protective factor for the prevention of anastomotic leakage (AL) after anterior resection. Its role in leakage recovery is unknown. This study aimed to evaluate the effect ...
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Article
Open AccessComparative study of single-center patients with thyroid metastases from colorectal cancer and previously reported cases in the literature
Thyroid metastases from colorectal cancer (CRC) are rare, both in clinical practice and in the literature; hence, their diagnosis, appropriate treatment, and prognostic factors require further investigations.
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Article
Prognostic risk factors in patients with bone metastasis from colorectal cancer
The morbidity of bone metastasis (BM) from colorectal cancer (CRC) is increasing more than ever; however, insufficient research on BM from CRC leads to reduced awareness of the issue. Therefore, the aim of thi...
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Article
Open AccessNeutrophil-to-lymphocyte and platelet-to-lymphocyte ratios predict chemotherapy outcomes and prognosis in patients with colorectal cancer and synchronous liver metastasis
Recent evidence indicates that inflammatory parameters could be useful to predict metastasis from colorectal cancer. However, their roles in predicting chemotherapy response and prognosis in patients with sync...
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Article
Open AccessNuclear-enriched abundant transcript 1 as a diagnostic and prognostic biomarker in colorectal cancer
High expression of the long non-coding RNA nuclear-enriched abundant transcript 1 (NEAT1) in whole blood has been reported in colorectal cancer patients; however, its’ clinical significance and origin are uncl...
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Article
Erratum to: Clinicopathological and genetic features of Chinese hereditary nonpolyposis colorectal cancer (HNPCC)
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Article
CXCL10 mRNA expression predicts response to neoadjuvant chemoradiotherapy in rectal cancer patients
Chemoradiotherapy has been commonly used as neoadjuvant therapy for rectal cancer to allow for less aggressive surgical approaches and to improve quality of life. In cancer, it has been reported that CXCL10 ha...
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Article
Open AccessClinicopathological and genetic features of Chinese hereditary nonpolyposis colorectal cancer (HNPCC)
The aim of this study was to investigate the clinical value of different criteria and to understand the relationship between genotype and phenotype in Chinese hereditary nonpolyposis colorectal cancer (HNPCC)....
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Article
Open AccessConcomitant boost IMRT-based neoadjuvant chemoradiotherapy for clinical stage II/III rectal adenocarcinoma: results of a phase II study
This study was designed to evaluate the efficacy and toxicities of concomitant boost intensity-modulated radiation therapy (IMRT) along with capecitabine and oxaliplatin, followed by a cycle of Xelox, in neoad...