-
Article
Open AccessWhy Probability isn’t Magic
“What data will show the truth?” is a fundamental question emerging early in any empirical investigation. From a statistical perspective, experimental design is the appropriate tool to address this question by...
-
Article
Open AccessEstimation of invasive Group B Streptococcus disease risk in young infants from case-control serological studies
Group B Streptococcus (GBS) infections are a major cause of invasive disease (IGbsD) in young infants and cause miscarriage and stillbirths. Immunization of pregnant women against GBS in addition to intrapartu...
-
Article
Isoseparation and robustness in parametric Bayesian inference
This paper introduces a new family of local density separations for assessing robustness of finite-dimensional Bayesian posterior inferences with respect to their priors. Unlike for their global equivalents, u...
-
Article
Open AccessDesign and conduct of Caudwell Xtreme Everest: an observational cohort study of variation in human adaptation to progressive environmental hypoxia
The physiological responses to hypoxaemia and cellular hypoxia are poorly understood, and inter-individual differences in performance at altitude and outcome in critical illness remain unexplained. We propose ...