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  1. Article

    Open Access

    Sex differences in long-term kidney fibrosis following neonatal nephron loss during ongoing nephrogenesis

    Clinical studies suggest that female sex plays a protective role in the development and progression of kidney disease. Recent experimental studies indicate that in male rats early nephron loss under ongoing ne...

    Carlos Menendez-Castro, Nada Cordasic in Molecular and Cellular Pediatrics (2023)

  2. Article

    Open Access

    High-resolution label-free map** of murine kidney vasculature by raster-scanning optoacoustic mesoscopy: an ex vivo study

    Chronic kidney disease (CKD) is a global burden affecting both children and adults. Novel imaging modalities hold great promise to visualize and quantify structural, functional, and molecular organ damage. The...

    Colin A. Goebel, Emma Brown, Fabian B. Fahlbusch in Molecular and Cellular Pediatrics (2022)

  3. Article

    Open Access

    Influence of labor on direct and indirect determinants of placental 11beta-hydroxysteroid dehydrogenase activity

    Labor is a complex process involving multiple para-, auto- and endocrine cascades. The interaction of cortisol, corticotropin-releasing hormone (CRH) and progesterone is essential. The action of cortisol on th...

    Hanna Huebner, Kirsten Heussner, Matthias Ruebner in Archives of Gynecology and Obstetrics (2021)

  4. Article

    Open Access

    Sex differences in the development of vascular and renal lesions in mice with a simultaneous deficiency of Apoe and the integrin chain Itga8

    Apoe-deficient (Apoe −/−) mice develop progressive atherosclerotic lesions with age but no severe renal pathology in the absence of additional challenges. We...

    Ines Marek, Maurizio Canu, Nada Cordasic, Manfred Rauh in Biology of Sex Differences (2017)

  5. Article

    Open Access

    Corticotropin-releasing hormone stimulates expression of leptin, 11beta-HSD2 and syncytin-1 in primary human trophoblasts

    The placental syncytiotrophoblast is the major source of maternal plasma corticotropin-releasing hormone (CRH) in the second half of pregnancy. Placental CRH exerts multiple functions in the maternal organism:...

    Fabian B Fahlbusch, Matthias Ruebner in Reproductive Biology and Endocrinology (2012)