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Article
Open AccessRepetitive transcranial magnetic stimulation in the treatment of resistant depression: changes of specific neurotransmitter precursor amino acids
Repetitive transcranial magnetic stimulation (rTMS) for treatment-resistant major depression offers an alternative therapy, since more than every third patient is not responding to adequate antidepressive trea...
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Article
Open AccessTreatment of patients with geriatric depression with repetitive transcranial magnetic stimulation
Repetitive transcranial magnetic stimulation (rTMS) has become a useful tool to treat different neuropsychiatric conditions such as depression, dementia and extrapyramidal syndromes insufficiently responding t...
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Article
Homocysteine but not neopterin declines in demented patients on B vitamins
Inflammation and immune system activation seem to play an important role in the development and progression of dementia. Hyperhomocysteinemia is common in various forms of dementia, and a significant relations...
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Article
Dopamine receptor agonists in current clinical use: comparative dopamine receptor binding profiles defined in the human striatum
The aim of this study was to compare dopamine receptor binding affinities of all currently approved dopamine receptor agonist treatments for Parkinson’s disease (PD) in human brain tissue. α-Dihydroergocrypti...
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Article
Treatment of chronic neuropathic pain after traumatic central cervical cord lesion with gabapentin
Central cord syndrome may be associated with severe pain, resistant to conventional pain therapy regimens. Chronic pain may be a persistent problem in rehabilitation of spinal cord injuries. These pain syndro...
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Article
Moderate hyperhomocysteinaemia and immune activation in Parkinson's disease
Moderate hyperhomocysteinaemia has been linked to an increased risk for cardiovascular diseases. Increased homocysteine concentrations may follow folate depletion due to insufficient dietary intake of the vit...
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Article
Increased neopterin production and tryptophan degradation in advanced Parkinson's disease
Large amounts of neopterin are produced by interferon-(IFN)-γ-stimulated human monocytes/macrophages, and increased neopterin concentrations indicate cellular immune activation. In parallel, IFN-γ induces ind...
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Article
Hyperhomocysteinemia in dementia
Hyperhomocysteinemia is a strong risk factor for atherosclerotic vascular disease, and elevated serum homocysteine is correlated with vitamin B deficiency. In this pilot study, significantly elevated homocyst...
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Article
Tryptophan degradation and immune activation in Alzheimer's disease
Alzheimer's disease (AD) is likely associated with systemic immune activation. During immune response, interferon-gamma stimu-lates indoleamine 2,3-dioxygenase (IDO) converting tryptophan to N-formylkynurenin...
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Degradation of Tryptophan in Neurodegenerative Disorders
In patients with neurodegenerative disorders, namely Alzheimer’s disease and Huntington’s disease, we compared serum concentrations of tryptophan, kynurenine and the kynurenine per tryptophan ratio with concen...
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Article
Correlations between mental state and quantitative neuropathology in the Vienna Longitudinal Study on Dementia
Quantitative clinicopathological correlation studies are one way to address the question of the relevance of morphological abnormalities in Alzheimer's dementia (AD). This paper summarizes results of the Vienn...
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Article
Age and sex differences of dehydroepiandrosterone sulfate (DHEAS) and cortisol (CRT) plasma levels in normal controls and Alzheimer's disease (AD)
In 50 healthy subjects (23 female, 27 male, aged 18–81) and 24 patients with Alzheimer's disease (AD) (11 female, 13 male, aged 58–88) DHEAS and CRT plasma levels were studied. In normal subjects there was a c...
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Article
Long latency EMG responses in early diagnosis of Huntington's chorea
In healthy subjects, 2 EMG responses of the thenar muscles can be distinguished, elicited by electrical stimulation of the median nerve during an isometric contraction: an early spinal response (M1) and a long la...
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Article
Asterixis as a side effect of carbamazepine therapy
A patient developed asterixis 13 weeks after starting a therapy with carbamazepine. Serum concentration of carbamazepine was within the therapeutic levels. Further factors which might have provoked asterixis w...
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Article
Single photon emission computed tomography in subjects at risk for Huntington's chorea
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Single photon emission computed tomography (SPECT) in Pick’s disease: two case reports
The diagnostic value of SPECT in Pick’s disease is discussed on the basis of two cases. Personality changes predominated in both of them. Atrophy of the frontal and temporal lobes was seen on CT only in one of...
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Article
Single photon emission computed tomography (SPECT) in probable Huntington's chorea (HC)
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Article
Genetic linkage studies in hereditary motor and sensory neuropathies
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Article
Carpal tunnel syndrome: Neurographical parameters in different stages of median nerve compression
In a series of 47 cases and 55 hands operated upon for carpal tunnel syndrome, the pre-operative electrodiagnostic findings have been compared retrospectively with the morphological findings within the carpal ...
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Article
Improvement of atactic syndrome after longer periods of alcohol abstinence
