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Article
Open AccessA phase I dose-finding and pharmacokinetic study of subcutaneous semisynthetic homoharringtonine (ssHHT) in patients with advanced acute myeloid leukaemia
To determine the maximum-tolerated dose (MTD), dose-limiting toxicities and pharmacokinetic of semisynthetic homoharringtonine (ssHHT), given as a twice daily subcutaneous (s.c.) injections for 9 days, in pati...
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Chapter and Conference Paper
Management of Fever in Adult Hematological Neutropenic Patients: Comparison of Tazocillin + Aminoside versus Ceftazidime + Aminoside in 466 Febrile Episodes
Two successive studies comparing tazocilline (12 g piperacillin + 1.5 g tazobactam/ day) + aminoside (15 mg/k/day amikacin in the first trial, 3 mg/kg/d tobramycin in the second) to ceftazidime (3 g/day) + ami...
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Article
Abstracts of papers and posters safe handling of medicines
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Chapter
Histamine in the Brain: Importance of Transmethylation Processes and Their Regulation
The physiological role of histamine in most mammalian tissues is at present a subject of controversy. However, thanks to the sophistication of the methods employed to study its metabolism and actions, data whi...