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Article
Open AccessDevelopment of secretome-based strategies to improve cell culture protocols in tissue engineering
Advances in skin tissue engineering have promoted the development of artificial skin substitutes to treat large burns and other major skin loss conditions. However, one of the main drawbacks to bioengineered s...
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Article
Open AccessCharacterization of the human ridged and non-ridged skin: a comprehensive histological, histochemical and immunohistochemical analysis
The structure of the human skin is directly dependent on its location and the mechanical forces to which it is subjected. In the present work, we have performed a comprehensive analysis of the human ridged and...
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Article
Open AccessCorrelations between plasma and PET beta-amyloid levels in individuals with subjective cognitive decline: the Fundació ACE Healthy Brain Initiative (FACEHBI)
Peripheral biomarkers that identify individuals at risk of develo** Alzheimer’s disease (AD) or predicting high amyloid beta (Aβ) brain burden would be highly valuable. To facilitate clinical trials of disea...
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Article
Wharton’s jelly-derived mesenchymal cells as a new source for the generation of microtissues for tissue engineering applications
Microtissues (MT) are currently considered as a promising alternative for the fabrication of natural, 3D biomimetic functional units for the construction of bio-artificial substitutes by tissue engineering (TE...
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Article
Open AccessHuman recombinant glutamate oxaloacetate transaminase 1 (GOT1) supplemented with oxaloacetate induces a protective effect after cerebral ischemia
Blood glutamate scavenging is a novel and attractive protecting strategy to reduce the excitotoxic effect of extracellular glutamate released during ischemic brain injury. Glutamate oxaloacetate transaminase 1...
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Article
Group 1 LEA proteins, an ancestral plant protein group, are also present in other eukaryotes, and in the archeae and bacteria domains
Water is an essential element for living organisms, such that various responses have evolved to withstand water deficit in all living species. The study of these responses in plants has had particular relevanc...
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Article
Central venous catheterization: a randomized comparison between external and internal jugular access
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Article
Central venous catheterization: a randomized comparison between external and internal jugular access
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Chapter and Conference Paper
Macroconduction and microconduction during rapid pacing measured with cardiac near field technique
Local conduction block may lead to wave breaks which are considered as organizing centers of cardiac arrhythmias. Sustained arrhythmias are associated with fast activation rates which in turn trigger adaptatio...
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Chapter and Conference Paper
Heterogeneity of Micro- and Macro-conduction in Atrial Pectinate Muscles studied with Cardiac Near Field Measurements and Computer Simulation
Macro- as well as micro-conduction of the cardiac impulse propagation in Pectinate muscles from Rabbit hearts is studied by means of experiments and by means of computer simulation. Two simultaneous recordings...
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Article
In vivo neurochemical characterization of Anatoxin-a evoked dopamine release from striatum
Anatoxin-a (AnTx) is a natural neurotoxin, which acts as a potent and stereoselective agonist at the nicotinic acetylcholine receptors. The in vivo actions of the AnTx on dopamine (DA) release are scarcely charac...
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Chapter and Conference Paper
MOGA-II for an Automotive Cooling Duct Optimization on Distributed Resources
In this paper a procedure for the multi-objective optimization of an automotive cooling duct is described. The two objectives considered are the minimization of the pressure drop between the inlet and the outl...
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Article
In vivo Effects of the Anatoxin-a on Striatal Dopamine Release
Anatoxin-a is an important neurotoxin that acts a potent nicotinic acetylcholine receptor agonist. This characteristic makes anatoxin-a an important tool for the study of nicotinic receptors. Anatoxin-a has be...
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Article
Effects of Manganese on Extracellular Levels of Dopamine in Rat Striatum: An Analysis In vivo by Brain Microdialysis
The aim of this study is to determine the effects of intrastriatal administration of MnCl2, on the extracellular levels of dopamine (DA) and metabolites dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (H...
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Article
Mechanisms Underlying Domoic Acid–Induced Dopamine Release from Striatum: An in Vivo Microdialysis Study
The brain microdialysis technique has been used to examine the in vivo effects of the neurotoxin domoic acid (an ionotropic glutamate receptor agonist) on dopamine (DA) release in the striatum of conscious and...
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Article
Acremonium strictum Pulmonary Infection in a Leukemic Patient Successfully Treated with Posaconazole After Failure of Amphotericin B
A severely neutropenic patient with chronic lymphocytic leukemia developed a diffuse bilateral pulmonary infection while receiving a therapeutic daily dosage of intravenous amphotericin B for Candida glabrata eso...
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Article
Second treatment with fludarabine in a Waldenström's macroglobulinemia patient
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Article
Lymphoma revealed by femoral fracture in a rheumatoid arthritis patient treated with methotrexate
The authors describe, in a female with rheumatoid arthritis (RA) treated by methotrexate (MTX), the occurence during walking of a left femoral shaft fracture. This middle third femoral fracture needed early in...
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Article
Toxicokinetics of 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) in the European corn borer,Ostrinia nubilalis (Hübner)
2,4-Dihydroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA), the major hydroxamic acid present in corn, and its tritiated derivative, were prepared synthetically for use in the determination of the toxicokinetics of...
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Article
Toxicity and toxicokinetics of 6-methoxybenzoxazolinone (MBOA) in the european corn borer,Ostrinia nubilalis (Hübner)
The maize-derived secondary chemical 6-methyoxybenzoxazoii-none (MBOA) and a tritiated derivative were prepared synthetically for a detailed examination of their toxicity and toxicokinetics in the European cor...
