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Moderate alcohol consumption is associated with improved insulin sensitivity, reduced basal insulin secretion rate and lower fasting glucagon concentration in healthy women
Moderate alcohol consumption is associated with a reduced risk of type 2 diabetes with a stronger effect in women. As the underlying mechanisms remain poorly characterised, we investigated its relationship wit...
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Risk factors for incident type 2 diabetes in individuals with a BMI of <27 kg/m2: the role of γ-glutamyltransferase. Data from an Epidemiological Study on the Insulin Resistance Syndrome (DESIR)
Risk factors for incident type 2 diabetes, in particular, hepatic markers, have rarely been studied in leaner individuals. We aimed to identify the metabolic and hepatic markers associated with incident diabet...
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Insulin pump failures are still frequent: a prospective study over 6 years from 2001 to 2007
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Nutritional intervention to reduce the n−6/n−3 fatty acid ratio increases adiponectin concentration and fatty acid oxidation in healthy subjects
Consumption of n−3 polyunsaturated fatty acids (PUFA) has a favourable impact on inflammation and cardiovascular disease. However, the Western diet is characterized by a low n−3 PUFA intake and an imbalance in th...
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40th EASD Annual Meeting of the European Association for the Study of Diabetes
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Irbesartan normalises the deficiency in glomerular nephrin expression in a model of diabetes and hypertension
Aims/hypothesis. The location of nephrin has been identified as the slit-diaphragm of the glomerular podocyte. Recent evidence suggests that nephrin could play a key role in the function of the g...
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Calcium-dependent low renin syndrome in a diabetic patient with prostaglandin deficiency
Calcium and prostaglandin are supposed to play a critical role in the renin-angiotensin aldosterone system. Calcium has been described as an inhibitory second messenger for renin exocytosis whereas vasodilator...
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Localization of human platelet proteoglycan gene to chromosome 10, band q22.1, by in situ hybridization
A cDNA probe of 527 base pairs coding for the human platelet proteoglycan (PPG) protein core demonstrated that the PPG gene lies on the long arm of chromosome 10, band q22.1. This result and other available da...