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Article
Citrate Uniport by the Mitochondrial Tricarboxylate Carrier: A Basis for a New Hypothesis for the Transport Mechanism
The tricarboxylate transport system located in the inner mitochondrial membrane was studied as an isolated protein reconstituted in proteoliposomes. The effects on the transport of citrate by various reagents,...
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Article
Functional properties of purified and reconstituted mitochondrial metabolite carriers
Eight mitochondrial carrier proteins were solubilized and purified in the authors' laboratories using variations of a general procedure based on hydroxyapatite and Celite chromatography. The molecular mass of ...
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Article
Transmembrane topology, genes, and biogenesis of the mitochondrial phosphate and oxoglutarate carriers
Phosphate and oxoglutarate carriers transport phosphate and oxoglutarate across the inner membranes of mitochondria in exchange for OH− and malate, respectively. Both carriers belong to the mitochondrial carrier ...
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Chapter and Conference Paper
Purification and Characterization of Three Mitochondrial Substrate Carriers: the Phosphate, the 2-Oxoglutarate and the Dicarboxylate Carriers
Since several substrates of the mitochondrial enzymes must be transported from the cytosol into the matrix and several products have to leave the mitochondria, the inner mitochondrial membrane has to be equipp...