33 Result(s)

Article

Glycemic control and cancer outcomes in oncologic patients with diabetes: an Italian Association of Medical Oncology (AIOM), Italian Association of Medical Diabetologists (AMD), Italian Society of Diabetology (SID), Italian Society of Endocrinology (SIE), Italian Society of Pharmacology (SIF) multidisciplinary critical view

Background: Increasing evidence suggests that diabetes increases the risk of develo** different types of cancer. Hyperinsulinemia, hyperglycemia and chronic inflammation, characteristic of diabetes, could re...

A. Natalicchio, N. Marrano, M. Montagnani… in Journal of Endocrinological Investigation (2024)

Article

Molecular profiling of pediatric and young adult colorectal cancer reveals a distinct genomic landscapes and potential therapeutic avenues

Colorectal cancer (CRC) is a global health concern, and the incidence of early onset (EO) CRC, has an upward trend. This study delves into the genomic landscape of EO-CRC, specifically focusing on pediatric (P...

A. Busico, P. Gasparini, E. Rausa, L. Cattaneo, F. Bozzi… in Scientific Reports (2024)

Article

Circulating miR-378 in plasma: a reliable, haemolysis-independent biomarker for colorectal cancer

Plasma circulating tumour-specific microRNAs (miRNAs) are promising biomarkers of tumour presence and recurrence, especially for diseases whose best chance of successful treatment requires early diagnosis and ...

S Zanutto, S Pizzamiglio, M Ghilotti, C Bertan, F Ravagnani… in British Journal of Cancer (2014)

Article

2.6 Cross-Sectional Analysis of Predictors of the Blood Pressure (BP) in Patients on Long-Term Haemodialysis (HD)

L. Vernaglione, F. Pennacchiotti… in High Blood Pressure & Cardiovascular Preve… (2007)

Article

A multicentre phase II study of carboplatin plus pegylated liposomal doxorubicin as first-line chemotherapy for patients with advanced or recurrent endometrial carcinoma: the END-1 study of the MITO (Multicentre Italian Trials in Ovarian Cancer and Gynecologic Malignancies) group

Anthracyclines and platinum derivates are active drugs for advanced endometrial carcinoma (AEC), but new schedules with higher efficacy and better tolerability are needed. A phase II study was conducted to des...

S Pignata, G Scambia, C Pisano, E Breda, M Di Maio, S Greggi… in British Journal of Cancer (2007)

Article

Is epirubicin effective in first-line chemotherapy of metastatic breast cancer (MBC) after an epirubicin-containing adjuvant treatment? A single centre phase III trial

The aim of the study was to demonstrate the superiority of docetaxel and epirubicin vs docetaxel alone as first-line therapy in metastatic breast cancer patients pretreated with adjuvant or neoadjuvant epirubicin...

C Pacilio, A Morabito, F Nuzzo, A Gravina, V Labonia, G Landi… in British Journal of Cancer (2006)

Article

Modulation of 5-fluorouracil as adjuvant systemic chemotherapy in colorectal cancer: the IGCS-COL multicentre, randomised, phase III study

The aims of this multicentre, randomised phase III trial were to evaluate: (1) the role of levamisol (LEV); and (2) the role of folinic acid (FA), added to 5-fluorouracil (5FU) in the adjuvant treatment of col...

S De Placido, M Lopez, C Carlomagno, G Paoletti, S Palazzo… in British Journal of Cancer (2005)

Article

A randomised clinical trial of two docetaxel regimens (weekly vs 3 week) in the second-line treatment of non-small-cell lung cancer. The DISTAL 01 study

Docetaxel (75 mg m⁻² 3-weekly) is standard second-line treatment in advanced non-small-cell lung cancer (NSCLC) with significant toxicity. To verify whether a weekly schedule (33.3 mg m⁻² for 6 weeks) improved qu...

C Gridelli, C Gallo, M Di Maio, E Barletta, A Illiano… in British Journal of Cancer (2004)

Article

Prevalence and management of pain in Italian patients with advanced non-small-cell lung cancer

Pain is a highly distressing symptom for patients with advanced cancer. WHO analgesic ladder is widely accepted as a guideline for its treatment. Our aim was to describe pain prevalence among patients diagnose...

M Di Maio, C Gridelli, C Gallo, L Manzione, L Brancaccio… in British Journal of Cancer (2004)

Article

Supportive care in patients with advanced non-small-cell lung cancer

The present study describes supportive care (SC) in patients with advanced non-small-cell lung cancer (NSCLC), evaluating whether it is affected by concomitant chemotherapy, patient's performance status (PS) a...

M Di Maio, F Perrone, C Gallo, R V Iaffaioli, L Manzione… in British Journal of Cancer (2003)

Article

Carboplatin plus paclitaxel in extensive small cell lung cancer: a multicentre phase 2 study

A multicentre phase 2 trial (single-stage design) was undertaken to test the efficacy and toxicity of carboplatin (AUC 6 according to Calvert) plus paclitaxel (175 mg/m² 3-h infusion) every 4 weeks in the first l...

C Gridelli, L Manzione, F Perrone, E Veltri, R Cioffi… in British Journal of Cancer (2001)

Article

Gemcitabine plus vinorelbine in advanced non-small cell lung cancer: a phase II study of three different doses

Our aim was to study the activity and toxicity of the gemcitabine plus vinorelbine (Gem Vin) combination and to identify the optimal dose. Previously untreated patients aged < 70 years, with stage IV or IIIb (...

C Gridelli, L Frontini, F Perrone, C Gallo, M Gulisano… in British Journal of Cancer (2000)