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Article
Dietary sodium restriction prevents vascular endothelial growth factor inhibitor-induced hypertension
Vascular endothelial growth factor inhibitors (VEGFIs) are effective anticancer agents which often induce hypertension. VEGFI-induced hypertension is sodium-sensitive in animal studies. Therefore, the efficacy...
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Article
Correction to: Outcomes of parathyroidectomy versus calcimimetics for secondary hyperparathyroidism and kidney transplantation: a propensity-matched analysis
An Erratum to this paper has been published: https://doi.org/10.1007/s00423-020-02046-z
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Article
Open AccessPotassium and the kidney: a reciprocal relationship with clinical relevance
By controlling urinary potassium excretion, the kidneys play a key role in maintaining whole-body potassium homeostasis. Conversely, low urinary potassium excretion (as a proxy for insufficient dietary intake)...
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Article
Open AccessPersonalized screening intervals for kidney function in patients with chronic heart failure: a modeling study
High mortality and rehospitalization rates demonstrate that improving risk assessment in heart failure patients remains challenging. Individual temporal evolution of kidney biomarkers is associated with poor c...
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Article
Open AccessEffect of sodium bicarbonate supplementation on the renin-angiotensin system in patients with chronic kidney disease and acidosis: a randomized clinical trial
Acidosis-induced kidney injury is mediated by the intrarenal renin-angiotensin system, for which urinary renin is a potential marker. Therefore, we hypothesized that sodium bicarbonate supplementation reduces ...
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Article
Open AccessLong-term prognosis after kidney donation: a propensity score matched comparison of living donors and non-donors from two population cohorts
Live donor nephrectomy is a safe procedure. However, long-term donor prognosis is debated, necessitating high-quality studies.
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Article
Open AccessCorrection to: Intravenous fluids: balancing solutions
In Table 3 on Page 486 the term osmolality should have read osmolarity.
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Article
Open AccessTiming of Parathyroidectomy Does Not Influence Renal Function After Kidney Transplantation
Parathyroidectomy (PTx) is the treatment of choice for end-stage renal disease (ESRD) patients with therapy-resistant hyperparathyroidism (HPT). The optimal timing of PTx for ESRD-related HPT—before or after k...
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Article
Open AccessSafety and efficacy of subtotal or total parathyroidectomy for patients with secondary or tertiary hyperparathyroidism in four academic centers in the Netherlands
Hyperparathyroidism (HPT) is a common abnormality in patients with end-stage renal disease (ESRD). Since the introduction of cinacalcet in 2004, a shift from surgery toward predominantly medical treatment has ...
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Article
Open AccessIntravenous fluids: balancing solutions
The topic of intravenous (IV) fluids may be regarded as “reverse nephrology”, because nephrologists usually treat to remove fluids rather than to infuse them. However, because nephrology is deeply rooted in fl...
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Article
Open AccessSerum magnesium and the risk of prediabetes: a population-based cohort study
Previous studies have found an association between serum magnesium and incident diabetes; however, this association may be due to reverse causation, whereby diabetes may induce urinary magnesium loss. In contr...
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Article
Open AccessFrom ARB to ARNI in Cardiovascular Control
Coexistence of hypertension, diabetes mellitus and chronic kidney disease synergistically aggravates the risk of cardiovascular and renal morbidity and mortality. These high-risk, multi-morbid patient populati...
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Article
Open AccessNeutrophil gelatinase-associated lipocalin (NGAL) predicts the occurrence of malaria-induced acute kidney injury
Acute kidney injury (AKI) is a frequently encountered complication of imported Plasmodium falciparum infection. Markers of structural kidney damage have been found to detect AKI earlier than serum creatinine-base...
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Article
Open AccessBone Mineral Density in Sjögren Syndrome Patients with and Without Distal Renal Tubular Acidosis
Primary Sjögren’s syndrome (pSS) can be complicated by distal renal tubular acidosis (dRTA), which may contribute to low bone mineral density (BMD). Our objective was to evaluate BMD in pSS patients with and ...
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Article
Open AccessLong-term changes in dysnatremia incidence in the ICU: a shift from hyponatremia to hypernatremia
Dysnatremia is associated with adverse outcome in critically ill patients. Changes in patients or treatment strategies may have affected the incidence of dysnatremia over time. We investigated long-term change...
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Article
Open AccessAcute kidney injury in imported Plasmodium falciparum malaria
Acute kidney injury (AKI) is a known complication of malaria, and is reported to occur in up to 40 % of adult patients with a severe Plasmodium falciparum infection in endemic regions. To gain insight in the inci...
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Article
Open AccessEverything you need to know about distal renal tubular acidosis in autoimmune disease
Renal acid–base homeostasis is a complex process, effectuated by bicarbonate reabsorption and acid secretion. Impairment of urinary acidification is called renal tubular acidosis (RTA). Distal renal tubular a...
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Article
Erratum to: Clinical practice guideline on diagnosis and treatment of hyponatraemia
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Article
Open AccessDistal renal tubular acidosis in primary Sjögren syndrome
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Article
Open AccessAldosterone does not require angiotensin II to activate NCC through a WNK4–SPAK–dependent pathway
We and others have recently shown that angiotensin II can activate the sodium chloride cotransporter (NCC) through a WNK4–SPAK-dependent pathway. Because WNK4 was previously shown to be a negative regulator of...
