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Article
Open AccessNeoadjuvant nivolumab or nivolumab plus LAG-3 inhibitor relatlimab in resectable esophageal/gastroesophageal junction cancer: a phase Ib trial and ctDNA analyses
Gastroesophageal cancer dynamics and drivers of clinical responses with immune checkpoint inhibitors (ICI) remain poorly understood. Potential synergistic activity of dual programmed cell death protein 1 (PD-1...
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Chapter
Staging Endoscopic Ultrasound
The role of endoscopic ultrasound (EUS) has evolved since its conception in the 1980s for not only diagnostic but also therapeutic purposes. It continues to be instrumental in the diagnosis, staging, and manag...
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Article
Open AccessAuthor Correction : SUPT4H1-edited stem cell therapy rescues neuronal dysfunction in a mouse model for Huntington’s disease
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Article
Open AccessSUPT4H1-edited stem cell therapy rescues neuronal dysfunction in a mouse model for Huntington’s disease
Huntington’s disease (HD) is a severe inherited neurological disorder caused by a CAG repeat expansion in the huntingtin gene (HTT), leading to the accumulation of mutant huntingtin with polyglutamine repeats. De...
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Article
Surgical Outcomes After Pancreatic Resection of Screening-Detected Lesions in Individuals at High Risk for Develo** Pancreatic Cancer
Screening high-risk individuals (HRI) can detect potentially curable pancreatic ductal adenocarcinoma (PDAC) and its precursors. We describe the outcomes of high-risk individuals (HRI) after pancreatic resecti...
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Chapter and Conference Paper
A Hepatoprotective Effect of a Hot Water Extract from Loliolus beka Gray Meat Against H2O2-Induced Oxidative Damage in Hepatocytes
Here, we investigated the hepatoprotective effect of a hot water extract from Loliolus beka gray meat (LBMH) containing plentiful taurine in H2O2-induced oxidative stress in hepatocytes. LBMH potently scavenged t...
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Chapter and Conference Paper
An Aqueous Extract of Octopus ocellatus Meat Protects Hepatocytes Against H2O2-Induced Oxidative Stress via the Regulation of Bcl-2/Bax Signaling
Octopus ocellatus meat (OM) is well known as a plentiful protein source. In this study, we evaluated the hepatoprotective effect of an aqueous extract of OM (OMA) against H2O2-triggered oxidative stress in human ...
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Chapter and Conference Paper
Hepatoprotective Activity of a Taurine-Rich Water Soluble Extract from Octopus vulgaris Meat
In this study, we investigated the hepatoprotective activity of the water extract derived from Octopus vulgaris meat (OM). First of all, a water extract prepared from OM (OMW) showed the high extraction yield (48...
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Chapter and Conference Paper
Cytoprotective Effects of an Aqueous Extracts from Atrina Pectinate Meat in H2O2-Induced Oxidative Stress in a Human Hepatocyte
In the present study, we investigated the antioxidant activity of an aqueous extract from Atrina pectinate meat (APW) against H2O2-induced oxidative stress in a human hepatocyte. The extraction yield of APW was 3...
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Chapter and Conference Paper
Protective Effect of Hot Water Extract of Loliolus Beka Gray Meat Against Palmitate-Induced HUVEC Damage
Endothelial dysfunction is a critical factor in the development of diabetes-mediated cardiovascular complications. Free fatty acids (FFA), such as palmitate, which are elevated in diabetes and obesity, have be...
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Chapter and Conference Paper
An Aqueous Extract from Batillus Cornutus Meat Protects Against H2O2-Mediated Cellular Damage via Up-Regulation of Nrf2/HO-1 Signal Pathway in Chang Cells
In this study, we evaluated the protective effects of an aqueous extract from Batillus cornutus meat (BM) against cellular oxidative damage caused by hydrogen peroxide (H2O2) in human hepatocyte, Chang cells. Fir...
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Chapter and Conference Paper
Hot Water Extract of Loliolus beka Meat Attenuates H2O2-Induced Damage in Human Umbilical Vein Endothelial Cells
Blood vessels become less flexible with senescence; arteries narrow and become less flexible, disturbing blood circulation in aging and other vascular diseases. Mechanistically, vascular senescence plays an im...
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Chapter and Conference Paper
Radio-Protective Effects of Loliolus beka Gray Meat Consisted of a Plentiful Taurine Against Damages Caused by Gamma Ray Irradiation
Gamma ray irradiation causes immune suppression, in which oxidative stress reduces cell viability and damages immune cells. In the present study, we investigated whether Loliolus beka gray meat (LBM), which conta...
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Chapter and Conference Paper
Antioxidant Effects of an Alcalase Hydrolysate from Batillus cornutus Meat
Batillus cornutus (B. cornutus) is one of the gastropoda, which are distributed along the coast of China, Japan and South Korea and northeast area. In this study, we first identified the antioxidant effects of a
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Article
A US Multicenter Study of Safety and Efficacy of Fully Covered Self-Expandable Metallic Stents in Benign Extrahepatic Biliary Strictures
Endoscopic therapy is considered first line for management of benign biliary strictures (BBSs). Placement of plastic stents has been effective but limited by their short-term patency and need for repeated proc...
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Article
Erratum to: Endoscopic ultrasound-guided fine needle aspiration improves the pre-operative diagnostic yield of solid-pseudopapillary neoplasm of the pancreas: an international multicenter case series (with video)
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Article
Endoscopic ultrasound-guided fine needle aspiration improves the pre-operative diagnostic yield of solid-pseudopapillary neoplasm of the pancreas: an international multicenter case series (with video)
Solid-pseudopapillary neoplasms (SPNs) are rare pancreatic tumors, which occur most frequently in young women and are associated with an excellent prognosis. Computed tomography (CT) is used most commonly to i...
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Article
Endoscopic stenting for benign upper gastrointestinal strictures and leaks
Self-expandable metal stents (SEMS) and self-expandable plastic stents (SEPS) maybe used for the treatment of benign upper gastrointestinal (GI) leaks and strictures. This study reviewed our experience with s...
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Article
Endoscopic ultrasound (EUS)-guided fiducial placement allows localization of small neuroendocrine tumors during parenchymal-sparing pancreatic surgery
Parenchymal-sparing pancreatic surgery is ideal for lesions such as small pancreatic neuroendocrine tumors (PanNET). However, precise localization of these small tumors at surgery can be difficult. The placeme...
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Article
Enteral stenting versus gastrojejunostomy for palliation of malignant gastric outlet obstruction
Endoscopic placement of enteral self-expandable metallic stents is an alternative to surgical gastrojejunostomy (GJ) for palliation of malignant gastric outlet obstruction (GOO). Factors associated with clinic...
