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  1. Article

    Open Access

    Effects of uric acid on ischemic diseases, stratified by lipid levels: a drug-target, nonlinear Mendelian randomization study

    Although uric acid-lowering agents such as xanthine oxidase inhibitors have potential cardioprotective effects, studies on their use in preventing cardiovascular diseases are lacking. We investigated the genet...

    Jungeun Kim, Sun Yeop Lee, Jihye Lee, Sanghyuk Yoon, Eun Gyo Kim in Scientific Reports (2024)

  2. Article

    Open Access

    A study of associations between CUBN, HNF1A, and LIPC gene polymorphisms and coronary artery disease

    The aim of this study was to identify novel genetic markers related to coronary artery disease (CAD) using a whole-exome sequencing (WES) approach and determine any associations between the selected gene polym...

    Han Sung Park, In Jai Kim, Eun Gyo Kim, Chang Soo Ryu, Jeong Yong Lee in Scientific Reports (2020)

  3. Article

    Open Access

    Genetic associations between the miRNA polymorphisms miR-130b (rs373001), miR-200b (rs7549819), and miR-495 (rs2281611) and colorectal cancer susceptibility

    Recent studies have extensively investigated the role of miRNAs in colorectal cancer (CRC), and several associations have been reported. In addition, single nucleotide polymorphisms (SNPs) in promoter regions ...

    Eun-Gyo Kim, Jung Oh Kim, Han Sung Park, Chang Soo Ryu, Jisu Oh, Hak Hoon Jun in BMC Cancer (2019)