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Article
Open AccessDisease-microenvironment modulation by bare- or engineered-exosome for rheumatoid arthritis treatment
Exosomes are extracellular vesicles secreted by eukaryotic cells and have been extensively studied for their surface markers and internal cargo with unique functions. A deeper understanding of exosomes has all...
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Article
Open AccessEffect of aging on the formation and growth of colonic epithelial organoids by changes in cell cycle arrest through TGF-β-Smad3 signaling
This study aimed to investigate how aging alters the homeostasis of the colonic intestinal epithelium and regeneration after tissue injury using organoid models and to identify its underlying molecular mechanism.
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Article
Modulation of gut microbiota by rice starch enzymatically modified using amylosucrase from Deinococcus geothermalis
Amylosucrase can increase the amount of resistant starch (RS) in starch by transferring glucose from sucrose to amylopectin. Here, rice starch was modified using amylosucrase from Deinococcus geothermalis (DgAS)....
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Chapter
Treatment Roadmap and Summaries
Breast cancer treatment is highly affected by the patient’s status of illness, overall health, and socioeconomic condition, but it is also influenced by the insurance policy of the society to which the patient...
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Chapter
Brief Overview of Breast Cancer Treatment
This chapter is a general overview briefly describing the treatment of breast cancer, intended to aid understanding of the various cases that will be mentioned in this book. Treatment for breast cancer include...
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Chapter
HR(+) HER2(+) Breast Cancer
Female/47 years old, pre-menopause.
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Chapter
HR(−) HER2(−) Breast Cancer
Female/40 years old, pre-menopause.
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Chapter
Metastatic Breast Cancer
Female/49 years old, post-menopause.
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Book
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Chapter
Detection and Diagnosis of Breast Cancer
This chapter is about the detection and diagnosis of breast cancer, serving as an introduction to help understand the breast cancer cases to be presented in the future. Breast cancer is the most common cancer ...
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Chapter
Carcinoma In Situ
Female/47 years old, pre-menopause.
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Chapter
Local Recurrence
Female/41 years old, pre-menopause.
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Article
Open AccessEffectiveness of the Korean National Cancer Screening Program in reducing breast cancer mortality
High incidences of breast cancer (BC) are reported in Asian women in their forties, and it is not clear whether mammographic screening reduces mortality among them. This study evaluated the effect of BC screen...
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Article
Analysis of the tumor characteristics in young age breast cancer patients using collaborative stage data of the Korea Central Cancer Registry
This study aimed to evaluate tumor characteristics in young age (20–39 years old) breast cancer (YABC) patients in Korea.
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Article
Open AccessSystematic evaluation of scoring methods for Ki67 as a surrogate for 21-gene recurrence score
Although Ki67 labeling index is a potential predictive marker for chemotherapy benefit, its clinical utility has been limited by the lack of a standard scoring method resulting in poor interobserver reproducib...
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Article
Open AccessCriteria for identifying residual tumours after neoadjuvant chemotherapy of breast cancers: a magnetic resonance imaging study
We investigated magnetic resonance imaging (MRI) criteria identifying residual tumours in patients with triple-negative and human epidermal growth factor receptor type 2-positive (HER2+) breast cancer followin...
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Article
Open AccessEfficacy of neoadjuvant endocrine therapy compared with neoadjuvant chemotherapy in pre-menopausal patients with oestrogen receptor-positive and HER2-negative, lymph node-positive breast cancer
Neoadjuvant endocrine therapy (NET) has demonstrated efficacy in post-menopausal patients with hormone-responsive breast cancer. This trial was designed to compare the efficacy of neoadjuvant chemotherapy (NCT...
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Article
Open AccessRole of aldehyde dehydrogenases, alcohol dehydrogenase 1B genotype, alcohol consumption, and their combination in breast cancer in East-Asian women
The associations between genetic polymorphisms in ADH1B (rs1229984) and ALDH2 (rs671), alcohol consumption, the effect of a combination of the two polymorphisms, and breast cancer risk were studied in a populatio...
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Article
Open AccessIdentification of novel breast cancer susceptibility loci in meta-analyses conducted among Asian and European descendants
Known risk variants explain only a small proportion of breast cancer heritability, particularly in Asian women. To search for additional genetic susceptibility loci for breast cancer, here we perform a meta-an...
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Article
Open AccessNight-shift work, circadian and melatonin pathway related genes and their interaction on breast cancer risk: evidence from a case-control study in Korean women
Our purpose is to investigate the impact of circadian and melatonin pathway genes as well as their interactions with night-shift work (NSW) on breast cancer risk in Korean women. Information about NSW and othe...
