6 Result(s)
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Protocol
Intracellular Calcium Recording After Purinoceptor Activation Using a Video-Microscopy Equipment
Calcium is one of the most important intracellular messengers, triggering a wide range of cellular responses. Changes in intracellular free calcium concentration can be measured using calcium sensitive fluores...
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Protocol
Time-Lapse Video Microscopy and Single Cell Tracking to Study Neural Cell Behavior In Vitro
A comprehensive understanding of the mechanisms controlling the behavior of cell populations with regenerative potential is the first step to design effective therapeutic strategies for many diseases. However,...
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Chapter
An Update on P2Y13 Receptor Signalling and Function
The distribution of nucleotide P2Y receptors across different tissues suggests that they fulfil key roles in a number of physiological and pathological conditions. P2Y13 is one of the latest P2Y receptors identif...
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Article
Open AccessP2X7, NMDA and BDNF receptors converge on GSK3 phosphorylation and cooperate to promote survival in cerebellar granule neurons
Glycogen synthase kinase-3 (GSK3) is a key player in the regulation of neuronal survival. Herein, we report evidence of an interaction between P2X7 receptors with NMDA and BDNF receptors at the level of GSK3 s...
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Chapter
Extracellular Signals and Transduction Mechanisms Controlling the Adenosine Transport in Neural Cells
The adenosine transport in bovine chromaffin cells is highly regulated by different extracellular signals, both at short and long-term. The short-term regulation by extracellular signals such as secretagogues ...
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Chapter
Control of Nucleoside Transport in Neural Cells Effect of Protein Kinase C Activation
Although nucleoside transport has been extensively characterized in synaptosomal preparations, they are not suitable for regulatory studies because the cellular integrity is necessary1,2. Adenosine transport is a...
