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    Article

    Integrative structure and functional anatomy of a nuclear pore complex

    Nuclear pore complexes play central roles as gatekeepers of RNA and protein transport between the cytoplasm and nucleoplasm. However, their large size and dynamic nature have impeded a full structural and func...

    Seung Joong Kim, Javier Fernandez-Martinez, Ilona Nudelman, Yi Shi, Wenzhu Zhang in Nature (2018)

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    HIV–host interactome revealed directly from infected cells

    Although genetically compact, HIV-1 commandeers vast arrays of cellular machinery to sustain and protect it during cycles of viral outgrowth. Transposon-mediated saturation linker scanning mutagenesis was used...

    Yang Luo, Erica Y. Jacobs, Todd M. Greco, Kevin D. Mohammed in Nature Microbiology (2016)