7 Result(s)
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Enkhjargal Tsend-Ayush
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Article
Open AccessMonotreme glucagon-like peptide-1 in venom and gut: one gene – two very different functions
The importance of Glucagon like peptide 1 (GLP-1) for metabolic control and insulin release sparked the evolution of genes mimicking GLP-1 action in venomous species (e.g. Exendin-4 in Heloderma suspectum (gila m...
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Article
Identification of mediator complex 26 (Crsp7) gametologs on platypus X1 and Y5 sex chromosomes: a candidate testis-determining gene in monotremes?
The basal lineage of monotremes features an extraordinarily complex sex chromosome system which has provided novel insights into the evolution of mammalian sex chromosomes. Recently, sequence information from ...
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Open AccessHigher-order genome organization in platypus and chicken sperm and repositioning of sex chromosomes during mammalian evolution
In mammals, chromosomes occupy defined positions in sperm, whereas previous work in chicken showed random chromosome distribution. Monotremes (platypus and echidnas) are the most basal group of living mammals....
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Erratum: Genome analysis of the platypus reveals unique signatures of evolution
Nature 453, 175–183 (2008) In this Article, Mikhail Nefedov and Pieter J. de Jong were omitted from the author list.
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Article
Open AccessThe multiple sex chromosomes of platypus and echidna are not completely identical and several share homology with the avian Z
Sex-determining systems have evolved independently in vertebrates. Placental mammals and marsupials have an XY system, birds have a ZW system. Reptiles and amphibians have different systems, including temperat...
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Article
Open AccessDisruption and pseudoautosomal localization of the major histocompatibility complex in monotremes
The monotremes, represented by the duck-billed platypus and the echidnas, are the most divergent species within mammals, featuring a flamboyant mix of reptilian, mammalian and specialized characteristics. To u...
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Article
In the platypus a meiotic chain of ten sex chromosomes shares genes with the bird Z and mammal X chromosomes
Two centuries after the duck-billed platypus was discovered, monotreme chromosome systems remain deeply puzzling. Karyotypes of males1, or of both sexes2,3,4, were claimed to contain several unpaired chromosomes ...
