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  1. Article

    Open Access

    Multi-technique comparison of atherogenic and MCD NASH models highlights changes in sphingolipid metabolism

    Lipotoxicity is a key player in the pathogenesis of nonalcoholic steatohepatitis (NASH), a progressive subtype of nonalcoholic fatty liver disease (NAFLD). In the present study, we combine histological, transc...

    Sophie A. Montandon, Emmanuel Somm, Ursula Loizides-Mangold… in Scientific Reports (2019)

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  2. Article

    Nicotinic Cholinergic Signaling in Adipose Tissue and Pancreatic Islets Biology: Revisited Function and Therapeutic Perspectives

    Nicotinic acetylcholine receptors (nAChRs) are membrane ligand-gated cation channels whose activation is triggered by the binding of the endogenous neurotransmitter acetylcholine or other biologic compounds in...

    Emmanuel Somm in Archivum Immunologiae et Therapiae Experimentalis (2014)

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  3. Article

    Definition and quantification of acute inflammatory white matter injury in the immature brain by MRI/MRS at high magnetic field

    Lipopolysaccharide (LPS) injection in the corpus callosum (CC) of rat pups results in diffuse white matter injury similar to the main neuropathology of preterm infants. The aim of this study was to characteriz...

    Gregory A. Lodygensky, Nicolas Kunz, Elodie Perroud, Emmanuel Somm… in Pediatric Research (2014)

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  4. Article

    Protective effects of maternal nutritional supplementation with lactoferrin on growth and brain metabolism

    Intrauterine growth restriction (IUGR) is a major risk factor for both perinatal and long-term morbidity. Bovine lactoferrin (bLf) is a major milk glycoprotein considered as a pleiotropic functional nutrient. ...

    Emmanuel Somm, Pierre Larvaron, Yohan van de Looij, Audrey Toulotte… in Pediatric Research (2014)

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