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    Article

    The raltitrexed-vinorelbine combination: a phase I pharmacokinetic and pharmacodynamic trial in advanced breast cancer

    Abstract

    Jean-Marc Ferrero, Emmanuel Chamorey, Nicolas Magné in Cancer Chemotherapy and Pharmacology (2002)

  2. No Access

    Article

    Use of the folinic acid/5-fluorouracil/irinotecan (FOLFIRI 1) regimen in elderly patients as a first-line treatment for metastatic colorectal cancer: a Phase II study

    The aim of this study was to evaluate the effects of a combination of folinic acid, 5-fluorouracil (5FU) and irinotecan (FOLFIRI 1) administered every 2 weeks in a population of elderly subjects with advanced ...

    Eric François, Jean-François Berdah in Cancer Chemotherapy and Pharmacology (2008)

  3. No Access

    Article

    Elevated basal antibody-dependent cell-mediated cytotoxicity (ADCC) and high epidermal growth factor receptor (EGFR) expression predict favourable outcome in patients with locally advanced head and neck cancer treated with cetuximab and radiotherapy

    Antibody-dependent cell-mediated cytotoxicity (ADCC) may contribute to the antitumor activity of cetuximab. However, the extent of this contribution is unclear. In this study, we investigated the impact of bas...

    Laura Lattanzio, Nerina Denaro, Daniela Vivenza in Cancer Immunology, Immunotherapy (2017)

  4. Article

    Open Access

    CXCL7 is a predictive marker of sunitinib efficacy in clear cell renal cell carcinomas

    Sunitinib is one of the first-line standard treatments for metastatic clear cell renal cell carcinoma (ccRCC) with a median time to progression shorter than 1 year. The objective is to discover predictive mark...

    Maeva Dufies, Sandy Giuliano, Julien Viotti in British Journal of Cancer (2017)

  5. No Access

    Article

    Germinal Immunogenetics predict treatment outcome for PD-1/PD-L1 checkpoint inhibitors

    Background Checkpoint inhibitors bring marked benefits but only in a minority of patients and may also be associated with severe adverse events. Treatment outcome still cannot be faithfully predicted. The followi...

    Sadal Refae, Jocelyn Gal, Nathalie Ebran, Josiane Otto in Investigational New Drugs (2020)

  6. Article

    Open Access

    DPD status and fluoropyrimidines-based treatment: high activity matters too

    Dihydropyrimidine dehydrogenase (DPD) status is an indicator of a marked risk for toxicity following fluoropyrimidine (FP)-based chemotherapy. This notion is well-established for low DPD status but little is k...

    Emmanuel Chamorey, Eric Francois, Marie-Christine Etienne, Jean-Marc Ferrero in BMC Cancer (2020)

  7. Article

    Correction to: Germinal Immunogenetics predict treatment outcome for PD-1/PD-L1 checkpoint inhibitors

    Corrections are needed to the original version of this article.

    Sadal Refae, Jocelyn Gal, Nathalie Ebran, Josiane Otto in Investigational New Drugs (2021)