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Dynamic epistasis analysis reveals how chromatin remodeling regulates transcriptional bursting

Transcriptional bursting has been linked to the stochastic positioning of nucleosomes. However, how bursting is regulated by the remodeling of promoter nucleosomes is unknown. Here, we use single-molecule live...

Ineke Brouwer, Emma Kerklingh, Fred van Leeuwen… in Nature Structural & Molecular Biology (2023)