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    Article

    In vitro cytotoxicity assessment of a West Virginia chemical spill mixture involving 4-methylcyclohexanemethanol and propylene glycol phenyl ether

    Thousands of gallons of industrial chemicals, crude 4-methylcyclohexanemethanol (MCHM) and propylene glycol phenyl ether (PPh), leaked from industrial tanks into the Elk River in Charleston, West Virginia, USA...

    Alice A. Han, Emily B. Fabyanic, Julie V. Miller in Environmental Monitoring and Assessment (2017)

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    Nondestructive, base-resolution sequencing of 5-hydroxymethylcytosine using a DNA deaminase

    A bisulfite-free sequencing method yields high-confidence 5hmC profiles in low-input samples.

    Emily K Schutsky, Jamie E DeNizio, Peng Hu, Monica Yun Liu in Nature Biotechnology (2018)

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    Joint single-cell profiling resolves 5mC and 5hmC and reveals their distinct gene regulatory effects

    Oxidative modification of 5-methylcytosine (5mC) by ten-eleven translocation (TET) DNA dioxygenases generates 5-hydroxymethylcytosine (5hmC), the most abundant form of oxidized 5mC. Existing single-cell bisulf...

    Emily B. Fabyanic, Peng Hu, Qi Qiu, Kiara N. Berríos in Nature Biotechnology (2024)