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    Chapter

    Opportunistic Infections Associated with Biologic Therapy

    Opportunistic infections are a severe complication in immunocompromised patients and in those receiving treatments that impair the homeostasis of the immunologic system. Biologics to treat autoimmune disorders...

    Emilio Martín-Mola, Chamaida Plasencia-Rodríguez in Infections and the Rheumatic Diseases (2019)

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    Article

    Color Doppler and spectral Doppler ultrasound detection of active sacroiliitis in spondyloarthritis compared to physical examination as gold standard

    Sacroiliac joint (SIJ) involvement is a distinctive feature of spondyloarthritis (SpA). The main objective of this study was to assess the validity of color Doppler ultrasound (CDUS) in SIJ. This was a cross-s...

    Concepción Castillo-Gallego, Eugenio De Miguel in Rheumatology International (2017)

  3. Article

    Open Access

    Constitutively altered frequencies of circulating follicullar helper T cell counterparts and their subsets in rheumatoid arthritis

    Circulating CD4 T cells expressing CXCR5, ICOS and/or PD-1 are counterparts of follicular helper T cells (Tfh). There are three subpopulations of circulating Tfh (cTfh): CXCR5 + CXCR3 + CCR6- (Tfh-Th1), CXCR5 ...

    Irene Arroyo-Villa, María-Belén Bautista-Caro in Arthritis Research & Therapy (2014)

  4. Article

    Open Access

    The immunogenicity to the first anti-TNF therapy determines the outcome of switching to a second anti-TNF therapy in spondyloarthritis patients

    Anti-TNF drugs have proven to be effective against spondyloarthritis (SpA), although 30% of patients fail to respond or experience adverse events leading to treatment discontinuation. In rheumatoid arthritis, ...

    Chamaida Plasencia, Dora Pascual-Salcedo in Arthritis Research & Therapy (2013)

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    Article

    Calprotectin in Rheumatoid Arthritis

    Calprotectin is potentially a more sensitive biomarker of disease activity in rheumatoid arthritis (RA) than conventional acute-phase proteins such as the erythrocyte sedimentation rate (ESR) and C-reactive pr...

    Miriam García-Arias, Dora Pascual-Salcedo, Susana Ramiro in Molecular Diagnosis & Therapy (2013)

  6. Article

    Open Access

    Influence of HLA DRB1 alleles in the susceptibility of rheumatoid arthritis and the regulation of antibodies against citrullinated proteins and rheumatoid factor

    The purpose of this study was to investigate the association between HLA-DRB1 alleles with susceptibility to rheumatoid arthritis (RA) and production of antibodies against citrullinated proteins (ACPA) and rhe...

    Alejandro Balsa, Arancha Cabezón, Gisela Orozco in Arthritis Research & Therapy (2010)