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Article
Second primary non-breast cancers in young breast cancer survivors
We evaluated the incidence, timing, and risk factors for second primary non-breast cancers (SPNBC) among young breast cancer (BC) survivors.
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Article
Patterns of treatment and outcomes of patients with brain-only metastatic breast cancer
We characterized the risk factors and survival of metastatic breast cancer (MBC) patients with brain metastases (BrM) as the first and only site of disease in a large, retrospective cohort.
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Article
Risk of recurrence and pregnancy outcomes in young women with breast cancer who do and do not undergo fertility preservation
To assess the impact of fertility preservation (FP) requiring ovarian stimulation on breast cancer outcomes and pregnancy after breast cancer.
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Article
Trastuzumab emtansine increases the risk of stereotactic radiosurgery-induced radionecrosis in HER2 + breast cancer
In this study, we investigate factors associated with radionecrosis (RN) in HER2 + (human epidermal growth factor receptor 2) patients with brain metastases (BrM) treated with stereotactic radiosurgery (SRS).
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Article
Risk factors for psychological morbidity and the protective role of co** self-efficacy in young women with breast cancer early in diagnosis: a national multicentre cohort study
Young women with breast cancer (YWBC) are an understudied population and there are limited data on risk factors for psychological morbidity early in diagnosis. We examined psychological morbidity (anxiety, dep...
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Article
Clinicopathological features and BRCA1 and BRCA2 mutation status in a prospective cohort of young women with breast cancer
Breast cancer in young women is more likely to have higher risk features and be associated with germline BRCA1/BRCA2 mutations. We present the clinicopathologic features of breast cancers in a prospective cohort ...
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Article
Open AccessCorrection to: Full population results from the core phase of CompLEEment-1, a phase 3b study of ribociclib plus letrozole as first-line therapy for advanced breast cancer in an expanded population
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Article
Open AccessReproductive concerns and fear of cancer recurrence: a qualitative study of women’s experiences of the perinatal period after cancer
Young female cancer survivors are at a disproportionate risk of suffering significant psychological distress following treatment, particularly fears of cancer recurrence (FCR). While previous research has esta...
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Article
Open AccessFull population results from the core phase of CompLEEment-1, a phase 3b study of ribociclib plus letrozole as first-line therapy for advanced breast cancer in an expanded population
CompLEEment-1 is a phase 3b trial in an expanded patient population with hormone receptor-positive (HR +), human epidermal growth factor receptor-2–negative (HER2–) advanced breast cancer (ABC), the largest cu...
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Article
Clinical outcomes and prognostic biomarkers among pregnant, post-partum and nulliparous women with breast cancer: a prospective cohort study
To compare clinical-pathologic characteristics and outcomes of pregnancy-associated, post-partum (PP) and nulliparous (NP) breast cancer (BC) patients and explore mediators of the poor prognosis associated wit...
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Article
Open AccessTreatment-related amenorrhea in a modern, prospective cohort study of young women with breast cancer
Young women with breast cancer experience unique treatment and survivorship issues centering on treatment-related amenorrhea (TRA), including fertility preservation and management of ovarian function as endocr...
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Article
Tumor phenotype and concordance in synchronous bilateral breast cancer in young women
Synchronous bilateral breast cancer is uncommon, and its pattern and incidence among younger women is unknown. Here we report the incidence, phenotypes, and long-term oncologic outcomes of bilateral breast can...
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Article
Infant feeding among women with a history of breast cancer
Health professional organizations recommend exclusive breastfeeding for 6 months, but there are mothers, such as those with a history of breast cancer, who are unable to exclusively provide their milk for thei...
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Chapter
Impact of MRI Screening on High-Risk Patient Outcome
This chapter tries to answer the crucial question: using breast MRI for screening, are we able to save lives of BRCA mutation carriers and other women at high risk? After discussing the intriguing difference betw...
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Article
Open AccessThe "Begin Exploring Fertility Options, Risks and Expectations" (BEFORE) decision aid: development and alpha testing of a fertility tool for premenopausal breast cancer patients
Premenopausal breast cancer patients are at risk of treatment-related infertility. Many patients do not receive sufficient fertility information before treatment. As such, our team developed and alpha tested the
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Chapter
Imaging Screening and Surveillance
BRCA mutation carriers, who have not undergone risk-reducing mastectomy by age 25–30, require annual screening with magnetic resonance imaging (MRI). Sensitivity of screening MRI in this population is 90...
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Article
Ten-year survival in women with primary stage IV breast cancer
To evaluate breast cancer-specific survival at 10 years in patients who present with primary stage IV breast cancer, and to determine whether survival varies with age of diagnosis.
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Article
Open AccessContribution of mammography to MRI screening in BRCA mutation carriers by BRCA status and age: individual patient data meta-analysis
We investigated the additional contribution of mammography to screening accuracy in BRCA1/2 mutation carriers screened with MRI at different ages using individual patient data from six high-risk screening trials.
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Article
A Metric for Reducing False Positives in the Computer-Aided Detection of Breast Cancer from Dynamic Contrast-Enhanced Magnetic Resonance Imaging Based Screening Examinations of High-Risk Women
Magnetic resonance imaging (MRI)-enabled cancer screening has been shown to be a highly sensitive method for the early detection of breast cancer. Computer-aided detection systems have the potential to improve...
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Article
Open AccessCouplelinks - an online intervention for young women with breast cancer and their male partners: study protocol for a randomized controlled trial
Young breast cancer survivors (aged 50 years and under) and their partners are at an elevated risk for relationship distress and poor psychological adjustment relative to older age couples. Limited availabilit...
