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  1. Article

    Open Access

    Health-related quality of life of children with X-linked hypophosphatemia in Germany

    X-linked hypophosphatemia (XLH) is a rare inherited phosphate-wasting disorder associated with bone and dental complications. Health-related quality of life (HRQoL) is reduced in XLH patients on conventional t...

    Martin Klein, Michael Obermaier, Helena Mutze, Sophia Maria Wilden in Pediatric Nephrology (2024)

  2. No Access

    Article

    Role of hypertension in progression of pediatric CKD

    Hypertension is frequent in children with chronic kidney disease (CKD). Its prevalence varies according to CKD stage and cause. It is relatively uncommon in children with congenital kidney disease, while acqui...

    Mark M. Mitsnefes, Elke Wühl in Pediatric Nephrology (2023)

  3. No Access

    Chapter

    Progression of Chronic Kidney Disease and Nephroprotective Therapy

    In childhood chronic kidney disease (CKD), progression towards kidney replacement therapy is common and once a significant impairment of kidney function has occurred, CKD tends to progress almost irrespectivel...

    Elke Wühl, Franz Schaefer in Pediatric Kidney Disease (2023)

  4. No Access

    Chapter

    Renal Hypertension: Etiology and Management

    The kidneys are key players in the homeostasis of blood pressure. In healthy subjects, the kidneys control both blood volume and vascular tone. Volume homeostasis is regulated by renal excretion of water and e...

    Elke Wühl, Franz Schaefer in Pediatric Kidney Disease (2023)

  5. No Access

    Reference Work Entry In depth

    Ambulatory Blood Pressure Monitoring Methodology and Norms in Children

    Over the last decades, ambulatory blood pressure monitoring (ABPM) has become the method of choice for the diagnosis and therapeutic monitoring of arterial hypertension in adult and pediatric patients. ABPM al...

    Elke Wühl in Pediatric Hypertension (2023)

  6. Article

    Definition, diagnosis and management of fetal lower urinary tract obstruction: consensus of the ERKNet CAKUT-Obstructive Uropathy Work Group

    Fetal lower urinary tract obstruction (LUTO) is associated with high mortality and postnatal morbidity caused by lung hypoplasia and impaired kidney function. Specific diagnostic features that can guide clinic...

    Valentina Capone, Nicola Persico, Alfredo Berrettini in Nature Reviews Urology (2022)

  7. No Access

    Reference Work Entry In depth

    Progression of Chronic Kidney Disease and Nephroprotection in Children

    Progression of chronic kidney disease (CKD) towards kidney replacement therapy is inevitable in some CKD patients and once significant impairment of kidney function has occurred it tends to progress almost irr...

    Elke Wühl, H. William Schnaper in Pediatric Nephrology (2022)

  8. No Access

    Living Reference Work Entry In depth

    Ambulatory Blood Pressure Monitoring Methodology and Norms in Children

    Over the last decades, ambulatory blood pressure monitoring (ABPM) has become a method of choice for the diagnosis and therapeutic monitoring of arterial hypertension in adult and pediatric patients. ABPM allo...

    Elke Wühl in Pediatric Hypertension

  9. No Access

    Living Reference Work Entry In depth

    Progression of Chronic Kidney Disease and Nephroprotection in Children

    Progression of chronic kidney disease (CKD) towards kidney replacement therapy is inevitable in some CKD patients and once significant impairment of kidney function has occurred it tends to progress almost irr...

    Elke Wühl, H. William Schnaper in Pediatric Nephrology

  10. No Access

    Chapter

    Management of Hypertension in Pediatric Dialysis Patients

    Hypertension is common among both peritoneal and hemodialysis patients. It is an important modifiable condition, and one of the most important contributors to the excess morbidity and mortality in this populat...

    Elke Wühl, Joseph T. Flynn in Pediatric Dialysis (2021)

  11. Article

    Open Access

    Severe neurological outcomes after very early bilateral nephrectomies in patients with autosomal recessive polycystic kidney disease (ARPKD)

    To test the association between bilateral nephrectomies in patients with autosomal recessive polycystic kidney disease (ARPKD) and long-term clinical outcome and to identify risk factors for severe outcomes, a...

    Kathrin Burgmaier, Gema Ariceta, Martin Bald, Anja Katrin Buescher in Scientific Reports (2020)

  12. No Access

    Article

    Sex and age as determinants for high blood pressure in pediatric renal transplant recipients: a longitudinal analysis of the CERTAIN Registry

    High prevalence of arterial hypertension is known in pediatric renal transplant patients, but how blood pressure (BP) distribution and control differ between age groups and whether sex and age interact and pot...

    Rizky I. Sugianto, Bernhard M. W. Schmidt, Nima Memaran, Ali Duzova in Pediatric Nephrology (2020)

  13. No Access

    Chapter

    Renale Hypertonie

    Die renale Hypertonie ist die häufigste Ursache einer sekundären Hypertonie im Kindesalter und liegt vor, wenn eine renoparenchymatöse oder renovaskuläre Erkrankung ursächlich für die Blutdruckerhöhung ist. Je...

    Elke Wühl in Pädiatrie (2020)

  14. Article

    Open Access

    Clinical practice recommendations for growth hormone treatment in children with chronic kidney disease

    Achieving normal growth is one of the most challenging problems in the management of children with chronic kidney disease (CKD). Treatment with recombinant human growth hormone (GH) promotes longitudinal growt...

    Jens Drube, Mandy Wan, Marjolein Bonthuis, Elke Wühl in Nature Reviews Nephrology (2019)

  15. Article

    Open Access

    Clinical courses and complications of young adults with Autosomal Recessive Polycystic Kidney Disease (ARPKD)

    Autosomal recessive polycystic kidney disease (ARPKD) is a severe pediatric hepatorenal disorder with pronounced phenotypic variability. A substantial number of patients with early diagnosis reaches adulthood ...

    Kathrin Burgmaier, Samuel Kilian, Bert Bammens, Thomas Benzing in Scientific Reports (2019)

  16. No Access

    Article

    Genetic associations of hemoglobin in children with chronic kidney disease in the PediGFR Consortium

    Genome-wide association studies (GWAS) in healthy populations have identified variants associated with erythrocyte traits, but genetic causes of hemoglobin variation in children with CKD are incompletely under...

    Meredith A. Atkinson, Rui **ao, Anna Köttgen, Elke Wühl in Pediatric Research (2019)

  17. No Access

    Article

    Steroid withdrawal improves blood pressure control and nocturnal dip** in pediatric renal transplant recipients: analysis of a prospective, randomized, controlled trial

    Variable effects of steroid minimization strategies on blood pressure in pediatric renal transplant recipients have been reported, but data on the effect of steroid withdrawal on ambulatory blood pressure and ...

    Britta Höcker, Lutz T. Weber, Ulrike John, Jens Drube in Pediatric Nephrology (2019)

  18. No Access

    Book

  19. No Access

    Living Reference Work Entry In depth

    Renale Hypertonie bei Kindern und Jugendlichen

    Die renale Hypertonie ist die häufigste Ursache einer sekundären Hypertonie im Kindesalter und liegt vor, wenn eine renoparenchymatöse oder renovaskuläre Erkrankung ursächlich für die Blutdruckerhöhung ist. Je...

    Elke Wühl in Pädiatrie

  20. No Access

    Chapter

    Treatment of Hypertension in Chronic Kidney Disease

    Renoparenchymal and renovascular disorders are the most common causes of secondary hypertension in childhood and adolescence, accounting for approximately 85% of cases. The prevalence of hypertension in pediat...

    Elke Wühl, Franz Schaefer in Hypertension in Children and Adolescents (2019)

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