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    Article

    Improvement in Motor Skills, Attention, and Working Memory in Mild Cognitive Impairment and Alzheimer’s Disease Patients Using COSMA Cognitive App

    There are a rapid growth of adults with cognitive impairments and an increasing need for cognitive stimulation and rehabilitation to delay cognitive deterioration. COSMA, a cognitive gaming app, was developed ...

    Aikaterini Christogianni, Kartheka Bojan in Augmented Human Research (2023)

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    Article

    Sex-disease dimorphism underpins enhanced motion sickness susceptibility in primary adrenal insufficiency: a cross-sectional observational study

    Environmental motion can induce physiological stress and trigger motion sickness. In these situations, lower-than-normal levels of adrenocorticotropic hormone (ACTH) have been linked with increased susceptibil...

    Yougan Saman, Mishaal Sharif, Abigail Lee, Shiza Ahmed in Experimental Brain Research (2023)

  3. Article

    Open Access

    Low levels of frailty in HIV-positive older adults on antiretroviral therapy in northern Tanzania

    There are over 3 million people in sub-Saharan Africa (SSA) aged 50 and over living with HIV. HIV and combined antiretroviral therapy (cART) exposure may accelerate the ageing in this population, and thus incr...

    Clare Bristow, Grace George, Grace Hillsmith, Emma Rainey in Journal of NeuroVirology (2021)

  4. Article

    Open Access

    Screening for HIV-Associated Neurocognitive Disorder (HAND) in Adults Aged 50 and Over Attending a Government HIV Clinic in Kilimanjaro, Tanzania. Comparison of the International HIV Dementia Scale (IHDS) and IDEA Six Item Dementia Screen

    Validated screening tools for HIV-associated neurocognitive disorders (HAND) are lacking for the newly emergent ageing population of people living with HIV (PLWH) in sub-Saharan Africa (SSA). We aimed to valid...

    Johanna Kellett-Wright, Aidan Flatt, Patrick Eaton, Sarah Urasa in AIDS and Behavior (2021)

  5. Article

    Open Access

    Re-examining tau-immunoreactive pathology in the population: granulovacuolar degeneration and neurofibrillary tangles

    Alzheimer’s disease (AD) is associated with neurofibrillary pathology, including neurofibrillary tangles (NFT), neuritic plaques (NP) and neuropil threads containing aggregated microtubule associated protein t...

    Sally Hunter, Thais Minett, Tuomo Polvikoski in Alzheimer's Research & Therapy (2015)

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    Article

    Deconstructing dementia and delirium hospital practice: using cultural historical activity theory to inform education approaches

    Older patients with dementia and delirium receive suboptimal hospital care. Policy calls for more effective education to address this though there is little consensus on what this entails. The purpose of this ...

    Andrew Teodorczuk, Elizabeta Mukaetova-Ladinska in Advances in Health Sciences Education (2015)

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    Article

    Systemic Neurochemical Alterations in Schizophrenic Brain: Glutamate Metabolism in Focus

    We have used a systemic approach to establish a relationship between enzyme measures of glial glutamate and energy metabolism (glutamine synthetase and glutamine synthetase-like protein, glutamate dehydrogenas...

    Gulnur Sh. Burbaeva, Irina S. Boksha, Elena B. Tereshkina in Neurochemical Research (2007)