6 Result(s)

Article

Vasculogenic mimicry in small cell lung cancer

Small cell lung cancer (SCLC) is characterized by prevalent circulating tumour cells (CTCs), early metastasis and poor prognosis. We show that SCLC patients (37/38) have rare CTC subpopulations co-expressing v...

Stuart C. Williamson, Robert L. Metcalf, Francesca Trapani… in Nature Communications (2016)

Article

Potential for the embryonic morphogen Nodal as a prognostic and predictive biomarker in breast cancer

The re-emergence of the tumour growth factor-beta (TGF-beta)-related embryonic morphogen Nodal has recently been reported in several different human cancers. In this study, we examined the expression of Nodal ...

Luigi Strizzi, Katharine M Hardy, Naira V Margaryan… in Breast Cancer Research (2012)

Article

Microenvironment alters epigenetic and gene expression profiles in Swarm rat chondrosarcoma tumors

Chondrosarcomas are malignant cartilage tumors that do not respond to traditional chemotherapy or radiation. The 5-year survival rate of histologic grade III chondrosarcoma is less than 30%. An animal model of...

Christopher A Hamm, Jeff W Stevens, Hehuang **e, Elio F Vanin… in BMC Cancer (2010)

Article

The Epigenetic Influence of Tumor and Embryonic Microenvironments: How Different are They?

The microenvironment is being increasingly recognized as a critical component in tumor progression and metastases. As such, the bi-directional signaling of extracellular mediators that promote tumor growth wit...

Daniel E. Abbott, Caleb M. Bailey, Lynne-Marie Postovit… in Cancer Microenvironment (2008)

Article

Molecular biology of breast cancer metastasis Molecular expression of vascular markers by aggressive breast cancer cells

During embryogenesis, the formation of primary vascular networks occurs via the processes of vasculogenesis and angiogenesis. In uveal melanoma, vasculogenic mimicry describes the 'embryonic-like' ability of a...

Mary JC Hendrix, Elisabeth A Seftor, Dawn A Kirschmann… in Breast Cancer Research (2000)

Article

An altered gene expression profile is associated with tumour vasculogenesis by human melanoma cells

Paul S. Meltzer, Andrew J. Maniotis, Robert Folberg, Angela Hess… in Nature Genetics (1999)