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Overview of Tumor Cells and the Microenvironment

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  1. Article

    Open Access

    Potential for the embryonic morphogen Nodal as a prognostic and predictive biomarker in breast cancer

    The re-emergence of the tumour growth factor-beta (TGF-beta)-related embryonic morphogen Nodal has recently been reported in several different human cancers. In this study, we examined the expression of Nodal ...

    Luigi Strizzi, Katharine M Hardy, Naira V Margaryan… in Breast Cancer Research (2012)

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  2. Article

    Open Access

    Microenvironment alters epigenetic and gene expression profiles in Swarm rat chondrosarcoma tumors

    Chondrosarcomas are malignant cartilage tumors that do not respond to traditional chemotherapy or radiation. The 5-year survival rate of histologic grade III chondrosarcoma is less than 30%. An animal model of...

    Christopher A Hamm, Jeff W Stevens, Hehuang **e, Elio F Vanin… in BMC Cancer (2010)

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  3. Article

    Molecular biology of breast cancer metastasis Molecular expression of vascular markers by aggressive breast cancer cells

    During embryogenesis, the formation of primary vascular networks occurs via the processes of vasculogenesis and angiogenesis. In uveal melanoma, vasculogenic mimicry describes the 'embryonic-like' ability of a...

    Mary JC Hendrix, Elisabeth A Seftor, Dawn A Kirschmann… in Breast Cancer Research (2000)

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