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  1. Article

    Open Access

    Leveraging the histidine kinase-phosphatase duality to sculpt two-component signaling

    Bacteria must constantly probe their environment for rapid adaptation, a crucial need most frequently served by two-component systems (TCS). As one component, sensor histidine kinases (SHK) control the phospho...

    Stefanie S. M. Meier, Elina Multamäki, Américo T. Ranzani in Nature Communications (2024)

  2. Article

    Open Access

    Comparative analysis of two paradigm bacteriophytochromes reveals opposite functionalities in two-component signaling

    Bacterial phytochrome photoreceptors usually belong to two-component signaling systems which transmit environmental stimuli to a response regulator through a histidine kinase domain. Phytochromes switch betwee...

    Elina Multamäki, Rahul Nanekar, Dmitry Morozov, Topias Lievonen in Nature Communications (2021)