10 Result(s)
within
Elena V. Romanova
Life Sciences
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Protocol
Nontargeted Identification of d-Amino Acid-Containing Peptides Through Enzymatic Screening, Chiral Amino Acid Analysis, and LC-MS
d-amino acid-containing peptides (DAACPs) in animals are a class of bioactive molecules formed via the posttranslational modification of peptides consisting of all-l-amino acid residues. Amino acid residue isomer...
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Protocol
Bioinformatics for Prohormone and Neuropeptide Discovery
Neuropeptides and peptide hormones are signaling molecules produced via complex posttranslational modifications of precursor proteins known as prohormones. Neuropeptides activate specific receptors and are ass...
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Article
Open AccessBiodistribution and racemization of gut-absorbed l/d-alanine in germ-free mice
Microbiome-derived metabolites are important for the microbiome-gut-brain axis and the discovery of new disease treatments. d-Alanine (d-Ala) is found in many animals as a potential co-agonist of the N-methyl-d-a...
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Article
Open AccessTranscriptomic plasticity of the hypothalamic osmoregulatory control centre of the Arabian dromedary camel
Water conservation is vital for life in the desert. The dromedary camel (Camelus dromedarius) produces low volumes of highly concentrated urine, more so when water is scarce, to conserve body water. Two hormones,...
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Article
Open AccessImage-guided MALDI mass spectrometry for high-throughput single-organelle characterization
Peptidergic dense-core vesicles are involved in packaging and releasing neuropeptides and peptide hormones—critical processes underlying brain, endocrine and exocrine function. Yet, the heterogeneity within th...
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Article
Open AccessGenetic diversity of SAD and FAD genes responsible for the fatty acid composition in flax cultivars and lines
Flax (Linum usitatissimum L.) is grown for fiber and seed in many countries. Flax cultivars differ in the oil composition and, depending on the ratio of fatty acids, are used in pharmaceutical, food, or paint ind...
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Protocol
Bioinformatics for Prohormone and Neuropeptide Discovery
Neuropeptides and peptide hormones are signaling molecules produced via complex post-translational modifications of precursor proteins known as prohormones. Neuropeptides activate specific receptors and are as...
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Article
Open AccessEvolution of mitochondrial genomes in Baikalian amphipods
Amphipods (Crustacea) of Lake Baikal are a very numerous and diverse group of invertebrates generally believed to have originated by adaptive radiation. The evolutionary history and phylogenetic relationships ...
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Article
Open AccessIdentification of prohormones and pituitary neuropeptides in the African cichlid, Astatotilapia burtoni
Cichlid fishes have evolved remarkably diverse reproductive, social, and feeding behaviors. Cell-to-cell signaling molecules, notably neuropeptides and peptide hormones, are known to regulate these behaviors a...
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Article
Profiling metabolites and peptides in single cells
The intracellular levels and spatial localizations of metabolites and peptides reflect the state of a cell and its relationship to its surrounding environment. Moreover, the amounts and dynamics of metabolites...
