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Open AccessKnockdown and overexpression of Unc-45b result in defective myofibril organization in skeletal muscles of zebrafish embryos
Unc-45 is a myosin chaperone and a Hsp90 co-chaperone that plays a key role in muscle development. Genetic and biochemical studies in C. elegans have demonstrated that Unc-45 facilitates the process of myosin fol...