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Chapter and Conference Paper
Wrong-Level Spine Surgery: Introduction of a Protocol for Avoidance of This Complication
Wrong-level spine surgery, in which an operation is performed at a vertebral level different from the intended one, is a rare but serious complication with wide-ranging medical and legal effects. Although many...
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Living Reference Work Entry In depth
Melanoma with Brain Metastasis
Melanoma is the third most common skin malignancy but is the one with the highest propensity to metastasize, potentially able to disseminate to any organ. Spreading to the central nervous system has been histo...
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Chapter
Gunshot Injuries to the Head
Traumatic brain injury (TBI) remains a major cause of death and disability worldwide, and missile-induced TBI remains the deadliest of all traumas since first reported and has always been associated with high ...
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Article
Hemorrhagic Complications of Invasive Intracranial Pressure Monitor Placement in Acute Liver Failure: Outcomes of a Single-Center Protocol and Comprehensive Literature Review
Elevated intracranial pressure due to cerebral edema is associated with very poor survival in patients with acute liver failure (ALF). Placing an intracranial pressure monitor (ICPm) aids in management of intr...
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Article
On the need of creating multicenter registries for more suitable matched cohort studies to elucidate best multidisciplinary care strategies for patients with Chiari malformations
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Article
Correction to: on the need of creating multicenter registries for more suitable matched cohort studies to elucidate best multidisciplinary care strategies for patients with Chiari malformations
A Correction to this paper has been published: https://doi.org/10.1007/s00701-021-04810-6
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Article
Feasibility, safety, and utility of brain MRI for patients with non-MRI-conditioned CIED
Feasibility, safety, and utility of brain MRI for patients with non-MRI-conditioned cardiac implantable electrical devices (CIEDs) remains controversial. While a growing number of studies have shown safe emplo...
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Article
Open AccessBRD4 prevents the accumulation of R-loops and protects against transcription–replication collision events and DNA damage
Proper chromatin function and maintenance of genomic stability depends on spatiotemporal coordination between the transcription and replication machinery. Loss of this coordination can lead to DNA damage from ...
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Article
Correction to: Clinical Chiari syndrome or anatomical Chiari malformation? A conundrum revisited
An incorrect set of affiliations for two authors (Tiit Illimar Mathiesen and Andreas K. Demetriades).
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Article
Clinical Chiari syndrome or anatomical Chiari malformation? A conundrum revisited
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Article
Chiari I malformation and pregnancy: a comprehensive review of the literature to address common questions and to guide management
The optimal management of Chiari I malformation during pregnancy remains uncertain. Labor contractions, which increase intracranial pressure, and neuraxial anesthesia both carry the theoretical risk of brainst...
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Article
Clinical outcomes following early versus late pharmacologic thromboprophylaxis in patients with traumatic intracranial hemorrhage: a systematic review and meta-analysis
Venous thromboembolism (VTE) after traumatic brain injury (TBI) with intracranial hemorrhage (ICH) presents a serious yet manageable morbidity and mortality risk. This systematic review and meta-analysis aimed...
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Article
Open AccessIndications, feasibility, safety, and efficacy of CyberKnife radiotherapy for the treatment of olfactory groove meningiomas: a single institutional retrospective series
To assess the safety and efficacy of CyberKnife® radiotherapy (CKRT) for the treatment of olfactory groove meningiomas (OGMs).
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Chapter
Hemispherical Cavernomas in Non-Eloquent and Eloquent Areas
Cerebral cavernoma are the most common clinically symptomatic vascular anomaly and constitute approximately 10%–15% of all vascular malformations. While the location of CCMs is quite variable, 70%–80% of CCMs ...
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Article
A Monoclonal Antibody Against β1 Integrin Inhibits Proliferation and Increases Survival in an Orthotopic Model of High-Grade Meningioma
High-grade meningiomas (HGMs; World Health Organization [WHO] classification grade II and III) have high relapse rates and poor clinical outcomes despite surgery and radiation treatments. No effective medical ...
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Article
Accelerated growth of hemangioblastoma in pregnancy: the role of proangiogenic factors and upregulation of hypoxia-inducible factor (HIF) in a non-oxygen-dependent pathway
Hemangioblastomas (HBs) are benign, highly vascular tumors, often characterized by loss of function of the von Hippel–Lindau (vHL) gene. They are the most common central nervous system tumor observed in vHL sy...
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Article
Spontaneous Intracranial Hemorrhage in Pregnancy: A Systematic Review of the Literature
Stroke in pregnant women has a mortality rate of 1.4 deaths per 100,000 deliveries. Vascular malformations are the most common cause of hemorrhagic stroke in this population; preeclampsia and other risk factor...
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Article
Granular cell tumor of the infundibulum: a systematic review of MR-radiography, pathology, and clinical findings
Granular cell tumors (GCTs) of the infundibulum are rare in practice and literature, resulting in a lack of evidence-based standard of care. We present two characteristic cases from our institution and perform...
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Article
Vascular hyperpermeability as a hallmark of phacomatoses: is the etiology angiogenesis comparable with mechanisms seen in inflammatory pathways? Part I: historical observations and clinical perspectives on the etiology of increased CSF protein levels, CSF clotting, and communicating hydrocephalus: a comprehensive review
Phacomatoses are a special group of familial hamartomatous syndromes with unique neuro-cutaneous manifestations as well as disease characteristic tumors. Neurofibromatosis 2 (NF2) and tuberous sclerosis comple...
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Article
Vascular hyperpermeability as a hallmark of phacomatoses: is the etiology angiogenesis related to or comparable with mechanisms seen in inflammatory pathways? Part II: angiogenesis- and inflammation-related molecular pathways, tumor-associated macrophages, and possible therapeutic implications: a comprehensive review
Phacomatoses are a special group of familial hamartomatous syndromes with unique neurocutaneous manifestations as well as characteristic tumors. Neurofibromatosis type 2 (NF2) and tuberous sclerosis complex (T...
