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Article
Open AccessLife-cycle-coupled evolution of mitosis in close relatives of animals
Eukaryotes have evolved towards one of two extremes along a spectrum of strategies for remodelling the nuclear envelope during cell division: disassembling the nuclear envelope in an open mitosis or constructi...
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Article
Open AccessPlasmodium ARK2 and EB1 drive unconventional spindle dynamics, during chromosome segregation in sexual transmission stages
The Aurora family of kinases orchestrates chromosome segregation and cytokinesis during cell division, with precise spatiotemporal regulation of its catalytic activities by distinct protein scaffolds. Plasmodium ...
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Article
Open AccessAuthor Correction: Genomic analysis finds no evidence of canonical eukaryotic DNA processing complexes in a free-living protist
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Article
Open AccessGenomic analysis finds no evidence of canonical eukaryotic DNA processing complexes in a free-living protist
Cells replicate and segregate their DNA with precision. Previous studies showed that these regulated cell-cycle processes were present in the last eukaryotic common ancestor and that their core molecular parts...
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Article
Open AccessThe molecular basis of monopolin recruitment to the kinetochore
The monopolin complex is a multifunctional molecular crosslinker, which in S. pombe binds and organises mitotic kinetochores to prevent aberrant kinetochore-microtubule interactions. In the budding yeast S. cerev...