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Open AccessTest characteristics of point-of-care ultrasonography in patients with acute kidney injury
Acute kidney injury is a common disorder that is associated with significant morbidity and mortality. Point-of-care ultrasonography (PoCUS) is an imaging modality performed at the bedside and is used to assess...
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Article
Open AccessReply to: “Is Prolonged Intermittent Renal Replacement Therapy actually safe for hemodynamically unstable patients?”
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Article
Open AccessHow I prescribe prolonged intermittent renal replacement therapy
Prolonged Intermittent Renal Replacement Therapy (PIRRT) is the term used to define ‘hybrid’ forms of renal replacement therapy. PIRRT can be provided using an intermittent hemodialysis machine or a continuous...
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Article
Delivering optimal renal replacement therapy to critically ill patients with acute kidney injury
Critical illness is often complicated by acute kidney injury (AKI). In patients with severe AKI, renal replacement therapy (RRT) is deployed to address metabolic dysfunction and volume excess until kidney func...
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Article
Open AccessIntravenous albumin for the prevention of hemodynamic instability during sustained low-efficiency dialysis: a randomized controlled feasibility trial (The SAFER-SLED Study)
Hemodynamic instability is a frequent complication of sustained low-efficiency dialysis (SLED) treatments in the ICU. Intravenous hyperoncotic albumin may prevent hypotension and facilitate ultrafiltration. In...
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Article
Open AccessIntra-dialytic hypotension following the transition from continuous to intermittent renal replacement therapy
Transition from continuous renal replacement therapy (CRRT) to intermittent renal replacement therapy (IRRT) can be associated with intra-dialytic hypotension (IDH) although data to inform the definition of ID...
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Article
Haemoperfusion should only be used for COVID-19 in the context of randomized trials
Interest in the use of haemoperfusion for severe COVID-19 has been spurred by anecdotal reports of its efficacy and expert reviews suggesting theoretical benefits. However, on the basis of the limited current ...
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Article
Open AccessDeath due to delirium: a case of a self-cut hemodialysis dialysis catheter - a case report
Neuropsychiatric conditions such as depression, delirium and cognitive impairment are common in patients with end-stage kidney disease (ESKD) and individuals suffering from ESKD are more likely to commit suici...
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Article
Open AccessMechanisms for hemodynamic instability related to renal replacement therapy: a narrative review
Hemodynamic instability related to renal replacement therapy (HIRRT) is a frequent complication of all renal replacement therapy (RRT) modalities commonly used in the intensive care unit. HIRRT is associated w...
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Open AccessSaline versus albumin fluid for extracorporeal removal with slow low-efficiency dialysis (SAFER-SLED): study protocol for a pilot trial
Critically ill patients frequently develop acute kidney injury that necessitates renal replacement therapy (RRT). At some centers, critically ill patients who are hemodynamically unstable and require RRT are t...
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Article
Open AccessOutcomes after toxic alcohol poisoning: a systematic review protocol
Toxic alcohols have been implicated in accidental ingestions and intentional exposures. Recognition of toxic alcohol poisoning is challenging. The main treatment modalities include antidotes with alcohol dehyd...
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Article
Open AccessSickle cell disease: a case report of renal amyloidosis
The development of proteinuria and reduced glomerular filtration rate is associated with higher mortality among patients with sickle cell disease (SCD). AA amyloidosis, also associated with increased mortality...
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Article
Implementation and evaluation of structured nephrology morbidity and mortality conferences: a quality education report
Morbidity and Mortality Conferences (M&MCs) have for generations been part of the education of physicians, yet their effectiveness remains questionable. The Ottawa M&M Model (OM3) was developed to provide a st...
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Open AccessInterventions to prevent hemodynamic instability during renal replacement therapy in critically ill patients: a systematic review
Hemodynamic instability related to renal replacement therapy (HIRRT) may increase the risk of death and limit renal recovery. Studies in end-stage renal disease populations on maintenance hemodialysis suggest ...
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Open AccessInterventions to prevent hemodynamic instability during renal replacement therapy for acute kidney injury: a systematic review protocol
Hemodynamic instability during renal replacement therapy (HIRRT) in the form of intradialytic hypotension (IDH) is a frequent complication of hemodialysis in end-stage kidney disease (ESKD), and most studies h...
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Article
Venous thromboembolism in chronic kidney disease: epidemiology, the role of proteinuria, CKD severity and therapeutics
The worldwide prevalence of chronic kidney disease is 10–15 % of the adult population, is rising and increases susceptibility to venous thromboembolism (VTE). In this narrative review we discuss the underlying...
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Open AccessGeographic and facility variation in initial use of non-tunneled catheters for incident maintenance hemodialysis patients
Non-tunneled (temporary) hemodialysis catheters (NTHCs) are the least-optimal initial vascular access for incident maintenance hemodialysis patients yet little is known about factors associated with NTHC use i...
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Article
Health-related quality-of-life among survivors of acute kidney injury in the intensive care unit: a systematic review
To summarize evidence on long-term health-related quality-of-life (HRQL) among survivors of acute kidney injury (AKI) in the intensive care unit (ICU).
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Open AccessUse of a national continuing medical education meeting to provide simulation-based training in temporary hemodialysis catheter insertion skills: a pre-test post-test study
Simulation-based-mastery-learning (SBML) is an effective method to train nephrology fellows to competently insert temporary, non-tunneled hemodialysis catheters (NTHCs). Previous studies of SBML for NTHC-inser...
