-
Article
Open AccessPrognostic implications of ΔNp73/TAp73 expression ratio in core-binding factor acute myeloid leukemia
-
Article
All-trans retinoic acid with daunorubicin or idarubicin for risk-adapted treatment of acute promyelocytic leukaemia: a matched-pair analysis of the PETHEMA LPA-2005 and IC-APL studies
Front-line treatment of acute promyelocytic leukaemia (APL) consists of all-trans retinoic acid (ATRA) and anthracycline-based chemotherapy. In this setting, a comparison of idarubicin and daunorubicin has never ...
-
Article
Internal tandem duplication of the FLT3 gene confers poor overall survival in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline-based chemotherapy: an International Consortium on Acute Promyelocytic Leukemia study
Activating internal tandem duplication (ITD) mutations in the fms-like tyrosine kinase 3 (FLT3) gene (FLT3-ITD) are associated with poor outcome in acute myeloid leukemia, but their prognostic impact in acute pro...
-
Article
Open AccessIncreased expression of miR-221 is associated with shorter overall survival in T-cell acute lymphoid leukemia
CD56 expression has been associated with a poor prognosis in lymphoid neoplasms, including T-cell acute lymphoblastic leukemia (T-ALL). MicroRNAs (miRNAs) play an important role in lymphoid differentiation, an...
-
Article
Acute promyelocytic leukemia associated with the PLZF-RARA fusion gene: two additional cases with clinical and laboratorial peculiar presentations
Acute promyelocytic leukemia (APL) is characterized by the presence of the t(15;17) and PML-RARa rearrangement, with good response to treatment with retinoids. However, few cases of variant APL involving alter...
-
Article
Cardiac stunning as a manifestation of ATRA differentiation syndrome in acute promyelocytic leukemia
-
Article
Erratum to: Results of FLT3 mutation screening and correlations with immunophenoty** in 169 Brazilian patients with acute myeloid leukemia
-
Article
Results of FLT3 mutation screening and correlations with immunophenoty** in 169 Brazilian patients with acute myeloid leukemia