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  1. No Access

    Article

    An optimal control problem applied to plasmid-mediated antibiotic resistance

    We formulate a system of ordinary differential equations to model the contribution of antibiotic treatment and immune system to combat bacterial infections. We obtained threshold conditions that determine when...

    Eduardo Ibargüen-Mondragón, Lourdes Esteva… in Journal of Applied Mathematics and Computi… (2022)

  2. No Access

    Article

    An optimal control problem and cost-effectiveness analysis of malaria disease with vertical transmission applied to San Andrés de Tumaco (Colombia)

    In this work, we studied malaria disease in San Andrés de Tumaco-Colombia (Tumaco) using mathematical modeling with the objective of contributing to the understanding its transmission dynamics and to the devel...

    Jhoana P. Romero-Leiton, Jairo Eloy Castellanos… in Computational and Applied Mathematics (2019)