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  1. No Access

    Article

    A phase 1 trial of adoptive transfer of vaccine-primed autologous circulating T cells in ovarian cancer

    We have previously shown that vaccination with tumor-pulsed dendritic cells amplifies neoantigen recognition in ovarian cancer. Here, in a phase 1 clinical study (NCT01312376

    Sara Bobisse, Valentina Bianchi, Janos L. Tanyi, Apostolos Sarivalasis in Nature Cancer (2023)

  2. Article

    Cutaneous presentation of enteropathy-associated T-cell lymphoma masquerading as a DUSP22-rearranged CD30+ lymphoproliferation

    DUSP22 gene rearrangements are recurrent in systemic and cutaneous ALK-negative anaplastic large cell lymphomas, rarely encountered in other cutaneous CD30+ lymphoproliferations, and typically absent in other per...

    Bettina Bisig, Anne Cairoli, Olivier Gaide, Joan Somja, Cloé Bregnard in Virchows Archiv (2022)

  3. Article

    Open Access

    CD73 expression in normal, hyperplastic, and neoplastic thyroid: a systematic evaluation revealing CD73 overexpression as a feature of papillary carcinomas

    CD73 converts AMP to adenosine, an immunosuppressive metabolite that promotes tumorigenesis. This study presents a systematic evaluation of CD73 expression in benign, hyperplastic, and neoplastic thyroid. CD73...

    Inês Monteiro, Edoardo Missiaglia, Amedeo Sciarra, João Vasco Santos in Virchows Archiv (2021)

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    Article

    Gallbladder Mixed Neuroendocrine-Non-neuroendocrine Neoplasm (MiNEN) Arising in Intracholecystic Papillary Neoplasm: Clinicopathologic and Molecular Analysis of a Case and Review of the Literature

    Mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs) of the gallbladder are generally composed of adenocarcinoma and neuroendocrine carcinoma (NEC). Rare cases associated with intracholecystic papillary ...

    Amedeo Sciarra, Edoardo Missiaglia, Mounir Trimech, Emmanuel Melloul in Endocrine Pathology (2020)

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    Article

    Acinar cell carcinoma of the pancreas with thyroid-like follicular features: first description of a new diagnostic challenging subtype

    Acinar cell carcinomas (ACCs) of the pancreas are a heterogeneous group of neoplasms showing a wide spectrum of morphological features including acinar, solid, glandular, and trabecular architecture. In additi...

    Chiara Saglietti, Vanessa Schneider, Massimo Bongiovanni in Virchows Archiv (2019)

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    Article

    Dual JAK1 and STAT3 mutations in a breast implant-associated anaplastic large cell lymphoma

    Audrey Letourneau, Marie Maerevoet, Dina Milowich, Roland Dewind in Virchows Archiv (2018)

  7. Article

    Open Access

    Type II enteropathy-associated T-cell lymphoma features a unique genomic profile with highly recurrent SETD2 alterations

    Enteropathy-associated T-cell lymphoma (EATL), a rare and aggressive intestinal malignancy of intraepithelial T lymphocytes, comprises two disease variants (EATL-I and EATL-II) differing in clinical characteri...

    Annalisa Roberti, Maria Pamela Dobay, Bettina Bisig, David Vallois in Nature Communications (2016)

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    Article

    The consensus molecular subtypes of colorectal cancer

    An international consortium of colorectal cancer researchers undertakes a large-scale data sharing project to achieve a consensus molecular classification of colorectal cancers.

    Justin Guinney, Rodrigo Dienstmann, **n Wang, Aurélien de Reyniès in Nature Medicine (2015)

  9. No Access

    Article

    Growth delay of human pancreatic cancer cells by methylase inhibitor 5-aza-2′-deoxycytidine treatment is associated with activation of the interferon signalling pathway

    Alteration of methylation status has been recognized as a possible epigenetic mechanism of selection during tumorigenesis in pancreatic cancer. This type of cancer is characterized by poor prognosis partly due...

    Edoardo Missiaglia, Massimo Donadelli, Marta Palmieri in Oncogene (2005)

  10. No Access

    Article

    Allelotype of ampulla of Vater cancer: highly frequent involvement of chromosome 11

    To determine the genetic differences/similarities in ampulla of Vater cancers (AVC) with respect to other pancreatic tumor types.

    Patrick S. Moore, Edoardo Missiaglia in Journal of Cancer Research and Clinical On… (2004)