-
Article
Open AccessLiver-directed treatment is associated with improved survival and increased response to immune checkpoint blockade in metastatic uveal melanoma: results from a retrospective multicenter trial
Metastases of uveal melanoma (UM) spread predominantly to the liver. Due to low response rates to systemic therapies, liver-directed therapies (LDT) are commonly used for tumor control. The impact of LDT on th...
-
Article
Naloxon als Rescue-Therapie bei akutem, schwerstem Pruritus
Zusammenfassend zeigte sich Naloxon in unserem Fall als schnelle, effektive Therapieoption bei massivem Pruritus auf primär unveränderter Haut, die letztendlich zu einer vollständigen Linderung des Juckempfind...
-
Article
Open AccessClinical determinants of long-term survival in metastatic uveal melanoma
This study aimed to identify prognostic factors in patients with metastatic uveal melanoma (UM) that were associated with long-term survival in a real-world setting. A total of 94 patients with metastatic UM w...
-
Article
Open AccessPatterns of care and follow-up care of patients with uveal melanoma in German-speaking countries: a multinational survey of the German Dermatologic Cooperative Oncology Group (DeCOG)
Uveal melanoma (UM) is an orphan cancer of high unmet medical need. Current patterns of care and surveillance remain unclear as they are situated in an interdisciplinary setting.
-
Article
Surgical site infections after microscopically controlled skin surgery in immunocompromised patients: a retrospective two-center cohort study
The data on the risk of surgical site infections (SSI) after skin surgery in patients undergoing immunosuppressive treatment are limited and the results of the existing single-center studies are controversial....
-
Article
Immune checkpoint blockade with concurrent electrochemotherapy in advanced melanoma: a retrospective multicenter analysis
Growing evidence suggests that concurrent loco-regional and systemic treatment modalities may lead to synergistic anti-tumor effects in advanced melanoma. In this retrospective multicenter study, we evaluate t...
-
Article
Open AccessOpen-label, multicenter, single-arm phase II DeCOG-study of ipilimumab in pretreated patients with different subtypes of metastatic melanoma
Ipilimumab is an approved immunotherapy that has shown an overall survival benefit in patients with cutaneous metastatic melanoma in two phase III trials. As results of registrational trials might not answer a...
-
Article
Immunoscreening of a cutaneous T-cell lymphoma library for plasma membrane proteins
Cutaneous T-cell lymphomas (CTCL) belong to non-Hodgkin lymphomas, which are primarily manifested in the skin and mostly exhibit a T-helper memory phenotype. Mycosis fungoides (MF) and the leukemic variant Séz...
-
Article
Exfoliatio areata linguae et mucosae oris: Eine Schleimhautmanifestation der Psoriasis pustulosa?
-
Article
Granulomatosis disciformis Miescher
-
Article
Zosteriformer Lichen aureus
-
Protocol
Nuclear Application of Antisense Oligonucleotides by Microinjection and Ballistomagnetic Transfer to Identify G Protein Heterotrimers Activating Phospholipase C
G proteins link heptahelical membrane receptors to their effector systems. The G proteins consist of three subunits, α, β, and γ, of which until now 23 (including splice variants), 6, and 11 different forms ar...
