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Article
Machine learning analysis of broadband optical reflectivity of semiconductor thin film
Broadband reflection spectroscopy is a non-invasive and non-contact tool widely used to measure optical dielectric constants and thickness of thin films. However, a lot of time and effort are consumed to analy...
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Article
Population-based, three-dimensional analysis of age- and sex-related femur shaft geometry differences
This study deals with differences of femoral geometric focus on the bowing and width. Analysis using three-dimensional skeletonization showed increase of femoral bowing and femur width over life (more in women...
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Article
Open AccessBlastocyst formation, embryo transfer and breed comparison in the first reported large scale cloning of camels
Cloning, through somatic cell nuclear transfer (SCNT), has the potential for a large expansion of genetically favorable traits in a population in a relatively short term. In the present study we aimed to produ...
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Article
A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer
The Kelch-like ECH-associated protein 1 (KEAP1)–nuclear factor E2-related factor 2 (NRF2)pathway has a central role in cellular antioxidant defense. NRF2 activation due to KEAP1 or NRF2 mutations occurs freque...
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Article
Open AccessStrong hole-do** and robust resistance-decrease in proton-irradiated graphene
Great effort has been devoted in recent years to improve the electrical conductivity of graphene for use in practical applications. Here, we demonstrate the hole carrier density of CVD graphene on a SiO2/Si subst...
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Article
hTERT mediates norepinephrine-induced Slug expression and ovarian cancer aggressiveness
Stress hormones have been implicated in both tumor initiation and progression. Human telomerase reverse transcriptase (hTERT) is overexpressed in cancer cells and associated with malignant tumor progression an...
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Article
Infrared conductivity of PED-grown (La,Ba)SnO3 thin films
We have synthesized La-doped BaSnO3 thin films on SrTiO3 substrates by using the pulsed electron deposition technique. By performing reflection/transmission measurements on the films and a Drude model analysis of...
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Article
Arginine methylation-dependent regulation of ASK1 signaling by PRMT1
Protein arginine methylation, catalyzed by protein arginine methyltransferases (PRMTs), is implicated in modulation of cellular processes including gene transcription. The role of PRMTs in the regulation of in...
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Article
Downregulation of Spry2 by miR-21 triggers malignancy in human gliomas
Gliomas are associated with high mortality because of their exceedingly invasive character. As these tumors acquire their invasiveness from low-grade tumors, it is very important to understand the detailed mol...
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Article
JIP1 binding to RBP-Jk mediates cross-talk between the Notch1 and JIP1-JNK signaling pathway
Notch1 signaling has a critical function in maintaining a balance among cell proliferation, differentiation, and apoptosis. Our earlier work showed that the Notch1 intracellular domain interferes with the scaf...
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Article
Genetic characterization of the Korean porcine reproductive and respiratory syndrome viruses based on the nucleocapsid protein gene (ORF7) sequences
To investigate the genetic characteristics of the Korean porcine reproductive and respiratory syndrome virus (PRRSV), we determined the complete sequence of the nucleocapsid protein gene (ORF7) from 105 PRRSV ...
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Article
Positive regulation of ASK1-mediated c-Jun NH2-terminal kinase signaling pathway by the WD-repeat protein Gemin5
Gemin5 is a 170-kDa WD-repeat-containing protein that was initially identified as a component of the survival of motor neurons (SMN) complex. We now show that Gemin5 facilitates the activation of apoptosis sig...
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Article
Gonadotropins in the Manchurian trout, Brachymystax lenok tsinlingensis
cDNA clones encoding gonadotropin (GTH) α, follicle-stimulating hormone (FSH) β and luteinzing hormone (LH) β were isolated from the pituitaries of maturing Manchurian trout (Brachymystax lenok tsinlingensis) and...
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Article
High glucose-induced intercellular adhesion molecule-1 (ICAM-1) expression through an osmotic effect in rat mesangial cells is PKC-NF-ϰB-dependent
Aims/hypothesis. Infiltration of mononuclear cells and glomerular enlargement accompanied by glomerular cell proliferation are very early characteristics of the pathophysiology of diabetes. To cl...
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Article
Cytotoxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin on primary cultures of adult rat hepatocytes
Primary cultures of adult rat hepatocytes were used to study the cytotoxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Rats were treated with a single oral dose of 5, 10 or 25Μg/kg of TCDD. At 2, 6, 10, 20,...
