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9 Result(s)

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  1. No Access

    Article

    Antioxidant capacity in rat brain after ICV treatment with streptozotocin and alloxan — a preliminary study

    Intracerebroventricular (icv) administration of betacytotoxic drug streptozotocin (STZ) produces long-term and progressive cognitive deficits in rats, as well as deficits in cerebral glucose and energy metabol...

    A. Sapcanin, E. Sofic, I. Tahirovic, M. Salkovic-Petrisic… in Neurotoxicity Research (2008)

  2. No Access

    Chapter and Conference Paper

    Brofaromine (CGP 11 305 A): estimation of plasma concentrations by a biologic technique as compared to liquid chromatography

    In an open clinical trial 13 depressives significantly improved under the reversible and selective type-A monoamine oxidase (MAO) inhibitor brofaromine. The inhibitory potency of deproteinated plasma on a crud...

    Dr. J. Fritze, Th. Becker, V. Ziegler… in Amine Oxidases and Their Impact on Neurobi… (1990)

  3. No Access

    Chapter and Conference Paper

    Clinical, biochemical and psychometric findings with the new MAO-A-inhibitors moclobemide and brofaromine in patients with major depressive disorder

    N = 53 inpatients with major depressive disorder have been treated with the reversible, selective MAO-A-inhibitors moclobemide (double-blind versus maprotiline) and brofaromine (open study), respectively. Clin...

    Dr. G. Laux, W. Classen, E. Sofic, T. Becker… in Amine Oxidases and Their Impact on Neurobi… (1990)

  4. No Access

    Chapter and Conference Paper

    Reflection of changes in membrane constituents in various regions of Alzheimer brains to differential scanning thermograms

    To test whether changes in basic biochemical membrane constituents were reflected in membrane fluidity measurements, protein, total lipids, triglycerides, lecithine, cholesterol and alkaline phosphatase were d...

    E. Sofic, M. Götz, Dr. L. Frölich, R. Burger… in Amine Oxidases and Their Impact on Neurobi… (1990)

  5. No Access

    Chapter and Conference Paper

    Urinary dopamine sulfate: regulations and significance in neurological disorders

    Dopamine-3-O-sulfate (DA-3-O-S) and dopamine-4-O-sulfate (DA-4-O-S) are important end products of L-dopa metabolism. Therefore they may give indications of disturbances in the peripheral metabolism of catechol...

    E. Kienzl, K. Eichinger, E. Sofic… in Amine Oxidases and Their Impact on Neurobi… (1990)

  6. No Access

    Article

    Plasma moclobemide and metabolites: lack of correlation with clinical response and biogenic amines

    The concentration of the reversible monoamine oxidase type-A (MAO-A) inhibitor moclobemide (Ro 11-1163) was determined by high pressure liquid chromatography (HPLC) in the plasma of 16 depressives treated with...

    J. Fritze, G. Laux, E. Sofic, P. Koronakis, M. P. Schoerlin… in Psychopharmacology (1989)

  7. No Access

    Book and Conference Proceedings

    The Role of Brain Dopamine

    P. Riederer, E. Sofic, C. Konradi, J. Kornhuber… in Basic and Clinical Aspects of Neuroscience (1989)

  8. No Access

    Chapter and Conference Paper

    Pathobiochemistry of the extrapyramidal system: a “short note” review

    Evidence is presented to show that in Parkinson’s disease (PD) there exists a topographical degeneration in the nigrostriatal dopamine system. This finding may account for response variabilities and side effec...

    Prof. Dr. P. Riederer, E. Sofic… in Early Diagnosis and Preventive Therapy in … (1989)

  9. No Access

    Chapter and Conference Paper

    The Role of Dopamine in the Control of Neurobiological Functions

    It is only 30 years since dopamine (DA) was first measured in human brain tissue by Sano [98] (Fig.1). One year later Ehringer and Hornykiewicz [34] demonstrated a striatal DA deficiency in Parkinson’s disease...

    P. Riederer, E. Sofic, C. Konradi, J. Kornhuber, H. Beckmann… in The Role of Brain Dopamine (1989)