26 Result(s)

Article

Insulin-requiring diabetes in rural Ethiopia: should we reopen the case for malnutrition-related diabetes?

We evaluated the incidence of insulin-requiring diabetes in a rural area of sub-Saharan Africa.

S. Alemu, A. Dessie, E. Seid, E. Bard, P. T. Lee, E. R. Trimble… in Diabetologia (2009)

Article

Glucose lowers the threshold for human aortic vascular smooth muscle cell migration: inhibition by protein phosphatase-2A

Atherosclerosis, which occurs prematurely in individuals with diabetes, incorporates vascular smooth muscle cell (VSMC) chemotaxis. Glucose, through protein kinase C-β_II signalling, increases chemotaxis to low co...

M. Campbell, P. Anderson, E. R. Trimble in Diabetologia (2008)

Article

40^th EASD Annual Meeting of the European Association for the Study of Diabetes

M. Veitenhansl, K. Stegner, F.-X. Hierl, C. Dieterle, H. Feldmeier, B. Gutt… in Diabetologia (2004)

Article

Diabetes-induced activation of protein kinase C inhibits store-operated Ca²⁺ uptake in rat retinal microvascular smooth muscle

To assess the effects of diabetes-induced activation of protein kinase C (PKC) on voltage-dependent and voltage-independent Ca²⁺ influx pathways in retinal microvascular smooth muscle cells.

T. M. Curtis, E. H. Major, E. R. Trimble, C. N. Scholfield PhD in Diabetologia (2003)

Article

Very low density lipoprotein subfractions in Type II diabetes mellitus: alterations in composition and susceptibility to oxidation

Aims/hypothesis. Type II (non-insulin-dependent) diabetes mellitus is associated with raised triglycerides and increased very low density lipoprotein cholesterol. The aim of this study was to ass...

J. McEneny, M. J. O'Kane, K. W. Moles, C. McMaster, D. McMaster, C. Mercer… in Diabetologia (2000)

Article

35th Annual Meeting of the European Association for the Study of Diabetes

A. Melander, J. Olsson, G. Lindberg, A. Salzman, T. Howard, P. Stang… in Diabetologia (1999)

Article

The effects of glucose-induced oxidative stress on growth and extracellular matrix gene expression of vascular smooth muscle cells

Vascular smooth muscle cell (VSMC) dysfunction plays a role in diabetic macrovasculopathy and this may include abnormalities in growth characteristics and the extracellular matrix. As the actual mechanisms by...

P. C. Sharpe, K. K. M. Yue, M. A. Catherwood, D. McMaster, E. R. Trimble in Diabetologia (1998)

Article

Contribution of glucose/glucose 6-phosphate cycle activity to insulin resistance in Type 2 (non-insulin-dependent) diabetes mellitus

It has been suggested that increased glucose/glucose 6-phosphate substrate cycling impairs net hepatic glucose uptake in Type 2 (non-insulin-dependent) diabetes mellitus and contributes to hyperglycaemia. To i...

D. P. Rooney, R. D. G. Neely, O. Beatty, N. P. Bell, B. Sheridan… in Diabetologia (1993)

Article

Royal Academy of Medicine in Ireland section of biological sciences Proceedings of Summer Meeting held at University of Ulster at Jordanstown, 22nd & 23rd June, 1990

J. M. Allen, A. A. Abu Shanab, D. J. S. Guthrie… in Irish Journal of Medical Science (1991)

Article

Underestimation of glucose turnover determined using [6-³H]glucose tracer in non-steady state

The use of tritiated glucose tracers may result in underestimation of glucose turnover during hyperinsulinaemic clamps giving paradoxical negative endogenous glucose production rates. While mathematical modell...

R. D. G. Neely, D. P. Rooney, A. B. Atkinson, B. Sheridan, C. N. Ennis… in Diabetologia (1990)