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  1. Article

    Open Access

    The specific metabolome profiling of patients infected by SARS-COV-2 supports the key role of tryptophan-nicotinamide pathway and cytosine metabolism

    The biological mechanisms involved in SARS-CoV-2 infection are only partially understood. Thus we explored the plasma metabolome of patients infected with SARS-CoV-2 to search for diagnostic and/or prognostic ...

    H. Blasco, C. Bessy, L. Plantier, A. Lefevre, E. Piver, L. Bernard… in Scientific Reports (2020)

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    Article

    Advances in Cellular Models to Explore the Pathophysiology of Amyotrophic Lateral Sclerosis

    Amyotrophic lateral sclerosis (ALS), the most common adult-onset motor neuron disorder, is fatal for most patients less than 3 years from when the first symptoms appear. The aetiologies for sporadic and most f...

    C. Veyrat-Durebex, P. Corcia, A. Dangoumau, F. Laumonnier… in Molecular Neurobiology (2014)

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    Article

    Cellular factors influencing Semliki Forest Virus vector biology

    Viral vectors are currently the best tools for gene delivery in a therapeutic setting, especially for in vivo use. Alphaviruses, a family of positive singlestranded RNA viruses, have been engineered to allow the ...

    E Piver, C Collin, A Diatta, P Vaudin, J-C Pagès in Gene Therapy (2005)