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  1. No Access

    Article

    Mucinous and non-mucinous colorectal cancers show differential expression of chemotherapy metabolism and resistance genes

    Previous research has identified differences in mutation frequency in genes implicated in chemotherapy resistance between mucinous and non-mucinous colorectal cancers (CRC). We hypothesized that outcomes in mu...

    E. O’Connell, I. S. Reynolds, M. Salvucci, D. A. McNamara… in The Pharmacogenomics Journal (2021)

  2. Article

    Open Access

    The novel toluidine sulphonamide EL102 shows pre-clinical in vitro and in vivo activity against prostate cancer and circumvents MDR1 resistance

    Taxanes are routinely used for the treatment of prostate cancer, however the majority of patients eventually develop resistance. We investigated the potential efficacy of EL102, a novel toluidine sulphonamide,...

    A P Toner, F McLaughlin, F J Giles, F J Sullivan, E O'Connell… in British Journal of Cancer (2013)

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