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  1. Article

    Open Access

    Clinical Oncogenomics and Personalized Medicine in Colorectal Cancer for the Surgeon: What We Need to Know and What the Future Holds

    Changes in the normal nucleotide sequence of the human genome plays an integral part in the development and progression of all cancers. It is now recognized that certain genomic alterations can be used to dete...

    I. S. Reynolds, E. O’Connell, D. A. McNamara… in SN Comprehensive Clinical Medicine (2022)

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  2. No Access

    Article

    Mucinous and non-mucinous colorectal cancers show differential expression of chemotherapy metabolism and resistance genes

    Previous research has identified differences in mutation frequency in genes implicated in chemotherapy resistance between mucinous and non-mucinous colorectal cancers (CRC). We hypothesized that outcomes in mu...

    E. O’Connell, I. S. Reynolds, M. Salvucci, D. A. McNamara… in The Pharmacogenomics Journal (2021)

  3. No Access

    Article

    Adherence to clinical guidelines and the potential economic benefits of admission avoidance for acute uncomplicated diverticulitis

    The treatment paradigm for acute diverticulitis is changing. There is an increasing trend towards managing patients with uncomplicated diverticulitis in the community.

    I. S. Reynolds, E. O’Connell, R. M. Heaney… in Irish Journal of Medical Science (1971 -) (2018)

  4. No Access

    Article

    Concussion in rugby: knowledge and attitudes of players

    Concussion is a traumatic brain injury, resulting in the alteration of mental status with or without loss of consciousness. There is increasing awareness that recurrent concussion may contribute to long-term n...

    E. O’Connell, M. G. Molloy in Irish Journal of Medical Science (1971 -) (2016)

  5. No Access

    Article

    Late cardiac effects of chemotherapy in breast cancer survivors treated with adjuvant doxorubicin: 10-year follow-up

    Doxorubicin (Dox), a mainstay of adjuvant breast cancer treatment, is associated with cardiac toxicity in the form of left ventricular dysfunction (LVD), LV diastolic dysfunction, or LV systolic dysfunction. S...

    G. Murtagh, T. Lyons, E. O’Connell, J. Ballot… in Breast Cancer Research and Treatment (2016)

  6. Article

    Open Access

    The novel toluidine sulphonamide EL102 shows pre-clinical in vitro and in vivo activity against prostate cancer and circumvents MDR1 resistance

    Taxanes are routinely used for the treatment of prostate cancer, however the majority of patients eventually develop resistance. We investigated the potential efficacy of EL102, a novel toluidine sulphonamide,...

    A P Toner, F McLaughlin, F J Giles, F J Sullivan, E O'Connell… in British Journal of Cancer (2013)

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  7. No Access

    Article

    Comparing the Tonojet disposable tonometer with the traditional Goldmann tonometer in glaucomatous and non-glaucomatous eyes

    Applanation tonometry is widely performed as the most accurate method of measuring intraocular pressure in the clinical setting. Disposable tonometer heads reduce the risk of transmitting infection during appl...

    S. M. J. Farrell, I. Dooley, E. O’Connell, S. Bashir… in International Ophthalmology (2013)

  8. No Access

    Article

    Visual outcomes and graft survival following corneal transplants: the need for an Irish National Corneal Transplant Registry

    To evaluate visual outcomes and corneal graft survival at 12 months postoperatively, and to demonstrate the need for an Irish National Corneal Transplant Registry.

    M. Guerin, E. O’ Connell, C. Walsh, T. Fulcher in Irish Journal of Medical Science (2008)

  9. Article

    The impact of new regulations on the incidence and severity of ocular injury sustained in hurling

    To prospectively evaluate, and compare, the incidence of hurling-related eye injuries in the South East of Ireland before and after implementation of new rules rendering the use of protective head gear and fac...

    M I Khan, T Flynn, E O'Connell, J Stack, S Beatty in Eye (2008)

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  10. No Access

    Article

    Eleventh all Ireland social medicine meeting

    J. Dunn-Lane, B. Herity, M. Moriarty, R. Conroy, F. Lee… in Irish Journal of Medical Science (1990)

  11. No Access

    Article

    Irish Paediatric Association

    R. McLoughlin, P. Geally, H. Monaghan, E. O’Connell… in Irish Journal of Medical Science (1989)