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Article
Open AccessHigh interindividual variability in LDL-cholesterol reductions after inclisiran administration in a real-world multicenter setting in Germany
Low-density lipoprotein cholesterol (LDL-C) is the main therapeutic target in the treatment of hypercholesterolemia. Small interfering RNA (siRNA) inclisiran is a new drug, which targets PCSK9 mRNA in the live...
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Article
Open AccessThe effect of an abdominal binder on postoperative outcome after open incisional hernia repair in sublay technique: a multicenter, randomized pilot trial (ABIHR-II)
Although the evidence is minimal, an abdominal binder is commonly prescribed after open incisional hernia repair (IHR) to reduce pain. This study aimed to investigate this common postoperative treatment.
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Article
Open AccessRobotic and laparoscopic liver resection—comparative experiences at a high-volume German academic center
Minimally invasive liver surgery (MILS) is a feasible and safe procedure for benign and malignant tumors. There has been an ongoing debate on whether conventional laparoscopic liver resection (LLR) or robotic ...
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Article
Open AccessA falciform ligament flap surface sealing technique for laparoscopic and robotic-assisted liver surgery
Whether sealing the hepatic resection surface after liver surgery decreases morbidity is still unclear. Nevertheless, various methods and materials are currently in use for this procedure. Here, we describe ou...
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Article
Erbrechen und Kollaps bei einem 28-jährigen Langstreckenläufer im mitteleuropäischen Sommer
Eine Hyperthermie endet nicht selten letal und muss daher umgehend erkannt und suffizient behandelt werden.
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Article
Open AccessAbstracts from the 4th ImmunoTherapy of Cancer Conference
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Article
Open AccessIncidentalomas during imaging for primary hyperparathyroidism—incidence and clinical outcomes
Imaging for pre-operative localisation of parathyroid glands in primary hyperparathyroidism is now routine. This has led to the detection of incidental lesions (incidentalomas) in other organs, the nature of w...
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Article
Kolmogorov spectrum of renewable wind and solar power fluctuations
With increasing the contribution of renewable energies in power production, the task of reducing dynamic instability in power grids must also be addressed from the generation side, because the power delivered ...
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Article
Very-high energy gamma-ray astronomy
Very-high energy (VHE) gamma quanta contribute only a minuscule fraction – below one per million – to the flux of cosmic rays. Nevertheless, being neutral particles they are currently the best “messengers” of ...
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Chapter
Bond Behavior of Textile Reinforcements - Development of a Pull-Out Test and Modeling of the Respective Bond versus Slip Relation
For strengthening existing concrete structures with textile reinforced concrete (TRC), anchoring of the TRC layer to the old concrete is crucial. Owing to their very high tensile strength, especially the ancho...
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Article
Open AccessDesign concepts for the Cherenkov Telescope Array CTA: an advanced facility for ground-based high-energy gamma-ray astronomy
Ground-based gamma-ray astronomy has had a major breakthrough with the impressive results obtained using systems of imaging atmospheric Cherenkov telescopes. Ground-based gamma-ray astronomy has a huge potenti...
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Chapter and Conference Paper
COAST: Modelling Restenosis and Stent Based Therapies
COAST (Complex Automata Simulation Technique) is a European Union FP6 funded project which has developed a methodology for multi-science, multi-scale simulation of complex systems. The resulting framework (MUS...
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Chapter
Space-Borne Autonomous On-Board Recognition of High Temperature Events
Satellite fire detection and monitoring observations are currently in an experimental or preoperational phase and directed to the development and testing of fire detection and analysis algorithms.
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Chapter
Wide Angle Air Cerenkov Detectors
For a number of important questions in VHE/UHE cosmic ray physics wide angle air Cerenkov detectors offer superior performance compared to scintillator arrays or air Cerenkov telescopes. On hand of the HEGRA a...
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Article
Wide angle air Cerenkov detectors
For a number of important questions in VHE/UHE cosmic ray physics wide angle air Cerenkov detectors offer superior performance compared to scintillator arrays or air Cerenkov telescopes. On hand of the HEGRA a...
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Chapter
The HEGRA Experiment
HEGRA is a large scintillation counter array for the observation of extended air showers. Details of the detector, its performance and initial results from a source search are presented. A short overview of th...
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Chapter and Conference Paper
Neue Trends in der lokoregionären Chemotherapie von Lebermetastasen
Regional chemotherapy in the treatment of nonresectable livermetastasis of colorectal carcinomas has been shown to be much more effective than systemic chemotherapy. To increase this effectivity, we implant a ...
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Article
Effect of oxygen on the formation of end-of-range disorder in implantation amorphized silicon
Formation of End-of-Range (EOR) disorder was studied in (100)-oriented silicon, when subjected to amorphization by implantation of Ge+ ions, followed by a 10 s Rapid Thermal Annealing (RTA) at 1050 °C. XTEM, RBS/...
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Chapter and Conference Paper
Chronic Energy Intake Restriction: Influence on Longevity, Autoimmunity, Immunodeficiency, and Cancer in Autoimmune-Prone Mice
The role of diet in the prevention of diseases of aging and the maintenance of good health has been the subject of great interest and much investigation in recent years. Over the past two decades we have inves...
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Chapter and Conference Paper
Pathogenese und stadiengerechte Therapie der aortointestinalen Fistel
Die obere gastrointestinale Blutung wird ätiologisch von den klassischen Blutungsursachen des Magens und des proximalen Duodenums bestimmt. In seltenen Fällen fulminanter Blutungsepisoden, die eine sofortige t...
