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Article
Functional Analysis and Molecular Modeling of a Cloned Urate Transporter/Channel
Recombinant protein, designated UAT, prepared from a cloned rat renal cDNA library functions as a selective voltage-sensitive urate transporter/channel when fused with lipid bilayers. Since we previously sugg...
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Article
Reconstitution of hepatic uricase in planar lipid bilayer reveals a functional organic anion channel
Rat renal proximal tubule cell membranes have been reported to contain uricase-like proteins that function as electrogenic urate transporters. Although uricase, per se, has only been detected within peroxisomes i...