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Article
Open AccessGDF15 linked to maternal risk of nausea and vomiting during pregnancy
GDF15, a hormone acting on the brainstem, has been implicated in the nausea and vomiting of pregnancy, including its most severe form, hyperemesis gravidarum (HG), but a full mechanistic understanding is lacking1
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Article
Open AccessUnderestimated risks of recurrent long-range ash dispersal from northern Pacific Arc volcanoes
Widespread ash dispersal poses a significant natural hazard to society, particularly in relation to disruption to aviation. Assessing the extent of the threat of far-travelled ash clouds on flight paths is sub...
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Article
A latent modeling approach to genotype–phenotype relationships: maternal problem behavior clusters, prenatal smoking, and MAOA genotype
This study illustrates the application of a latent modeling approach to genotype–phenotype relationships and gene × environment interactions, using a novel, multidimensional model of adult female problem behav...
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Article
Open AccessLiver transplantation in the critically ill: a Canadian collaboration
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Article
An in-frame deletion in the α2C adrenergic receptor is common in African–Americans
α2 adrenergic receptors are activated by adrenaline and noradrenaline, and three subtypes (ie, A, B, C) have differential affinities for antagonists and medications. The α2c adrenergic receptor (ADRA2C), located ...
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Article
Trans-Tasman Sea climate variability since ad 1740 inferred from middle to high latitude tree-ring data
The limited length and spatial coverage of instrumental climate data for many areas of the Southern Hemisphere impedes the study of atmosphere-ocean dynamics prior to the past century. Such analyses are impor...
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Some Historical Background on Dendrochronology
The systematic study of tree rings in western North America began with an intuitive insight by an astronomer, Andrew Ellicott Douglass. He was, before the turn of the 20th century, working at the Lowell Observ...
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Data Analysis
The information contained in annual tree rings is a valuable resource for studying environmental change. Past climate can be reconstructed from the yearto-year changes in annual ring width and ring density (e....
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Tree-Ring/Environment Interactions and Their Assessment
It is well known from history and prehistory that there are close relationships between environmental changes and the social, cultural, and economic development within a region. However, environmental impact a...