Skip to main content

5 Result(s)

within E. Aubrey Thompson Remove this filter English Remove this filter Life Sciences, general Remove this filter

and

  1. No Access

    Article

    Distinct E-cadherin-based complexes regulate cell behaviour through miRNA processing or Src and p120 catenin activity

    E-cadherin and p120 catenin (p120) are essential for epithelial homeostasis, but can also exert pro-tumorigenic activities. Here, we resolve this apparent paradox by identifying two spatially and functionally ...

    Antonis Kourtidis, Siu P. Ngok, Pamela Pulimeno, Ryan W. Feathers… in Nature Cell Biology (2015)

  2. Article

    Open Access

    3' tag digital gene expression profiling of human brain and universal reference RNA using Illumina Genome Analyzer

    Massive parallel sequencing has the potential to replace microarrays as the method for transcriptome profiling. Currently there are two protocols: full-length RNA sequencing (RNA-SEQ) and 3'-tag digital gene e...

    Yan W Asmann, Eric W Klee, E Aubrey Thompson, Edith A Perez, Sumit Middha… in BMC Genomics (2009)

    Download PDF (1065 KB) View Article

  3. No Access

    Article

    Akt interacts directly with Smad3 to regulate the sensitivity to TGF-β-induced apoptosis

    Transforming growth factor β (TGF-β) induces both apoptosis and cell-cycle arrest in some cell lines, but only growth arrest in others1. It is not clear how this differential response to TGF-β is specified. Smad ...

    Andrew R. Conery, Yanna Cao, E. Aubrey Thompson… in Nature Cell Biology (2004)

  4. No Access

    Chapter

    Glucocorticoid Regulation of Cell Proliferation

    Initiation of DNA replication in non-embryonic cells requires passage through an irreversible step in late Gl that has come to be called the restriction point. The restriction point was originally defined as t...

    E. Aubrey Thompson in Steroid Hormones and Cell Cycle Regulation (2002)

  5. No Access

    Chapter

    TGF-β Inhibition of Intestinal Epithelial Cell Proliferation: G1 Cyclins, Cyclin-Dependent Kinases, and Cyclin Kinase Inhibitors

    Colon carcinogenesis is a multistep process involving alterations in the normal replication of intestinal epithelial cells Vogelstein et al., 1988; Cameron et al., 1990; Vogelstein, 1990. In recent years, ther...

    E. Aubrey Thompson, Tien C. Ko, R. Daniel Beauchamp in Hormones and Cancer (1996)