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Introductory address for the 2014 John Howland award recipient, Rebecca H. Buckley
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Joseph A. Bellanti (ed) Immunology IV: Clinical Applications in Health and Disease
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Immunologic reconstitution in 22q deletion (DiGeorge) syndrome
Adoptive transfer of mature T cells (ATMTC) through bone marrow (BM) transplantation, first attempted over 20 years ago, has recently emerged as a successful therapy for complete 22q deletion syndrome (22qDS)....
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Robert A Good and Ludwig van Beethoven: Immortal Beloveds
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A History of Pediatric Immunology
Immunology has played a prominent role in the history of medicine. Pediatric immunologists have focused on immune aberrations in pediatric disorders, particularly those involving host defense mechanisms. These...
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Breast Milk Transmission of Viral Disease
Breast-feeding is, in general, nutritionally ideal, economically sound, immunologically advantageous, hygienically sterile and emotionally satisfying. Nevertheless, in certain maternal viral illnesses there is...
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New Directions in Immunoglobulin Therapy
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Human Hyperimmune HIV Intravenous Immunoglobulin (HIV-IG) in the Treatment of HIV-1 Infection in Children (PACTG-273)
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Effect of Interleukin (IL)-12 and IL-15 on Activated Natural Killer (ANK) and Antibody-Dependent Cellular Cytotoxicity (ADCC) in HIV Infection
The ability of IL-12 and IL-15 to enhance natural killer (NK) activity and antibody-dependent cellular cytotoxicity (ADCC) of mononuclear cells (MNCs) from HIV+ children and their mothers was investigated. MNCs f...
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Partially Mismatched Cord Blood Transplantation In X-Linked Immunodeficiencies • 44
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Subcutaneous Human Intravenous Immunoglobulin (IVIG) in the Treatment of Antibody Deficiency. ♦ 60
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ENHANCEMENT OF GP120-SPECIFIC CELL-MEDIATED CYTOTOXICITY (CMC) BY HIV HYPERIMMUNE INTRAVENOUS IMMUNOGLOBULIN (HIVIG)-ARMED EFFECTOR CELLS. † 1049
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SELECTIVE IgA DEFICIENCY AND HYPOGAMMAGLOBULINEMIA IN 4p - (WOLF-HIRSHHORN) SYNDROME. • 51
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SUCCESSFUL BONE MARROW TRANSPLANT (BMT) IN SEVERE COMBINED IMMUNODEFICIENCY(SCID) FROM A SIBLING WHO HAD RECEIVED A PATERNAL HAPLOIDENTICAL BMT FOR SCID.• 71
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INTERLEUKIN-2 (IL-2) AND IL-12 ENHANCE HIV GP120-SPECIFIC CELL-MEDIATED CYTOTOXICITY (CMC) OF MONONUCLEAR CELLS FROM HIV-INFECTED(HIV+) PATIENTS.† 58
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Antiviral Properties of Neonatal and Adult Human Neutrophils
ABSTRACT: The antiviral properties of neonatal and adult human neutrophils were investigated by their ability to inhibit the formation of herpes simplex virus (HSV) plaques using extrinsic viral resistance (EV...
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In Vitro Insulin-Like Growth Factor-I, Growth Hormone, and Insulin Resistance Occurs in Symptomatic Human Immunodeficiency Virus-1–Infected Children
ABSTRACT: Poor growth is a common feature of symptomatic children (Centers for Disease Control stage P2) infected with human immunodeficiency virus-1 (HIV-1). However, several previous studies have failed to s...
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New and Old Immunodeficiencies
ABSTRACT: Yesterday's immunodeficiencies emphasized the clinical and familial associations of the syndromes and date from the 1920s (ataxia-telangiectasia, chronic mucocutaneous candidiasis), the 1930s (Wiskot...
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Role of oxygen intermediates in cytotoxicity: Studies in chronic granulomatous disease
The ability of human neutrophils to lyse various target cells was investigated using cells from normal individuals and from patients with chronic granulomatous disease (CGD) whose cells lack the ability to for...
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Enhancement of normal neutrophil chemiluminescence by chronic granulomatous disease neutrophils
Neutrophils and other phagocytic cells from patients with chronic granulomatous disease (CGD) lack the ability to generate reactive oxygen intermediates (ROI), although other phagocytic functions appear to be ...