![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Open AccessColorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix
Citrullination of proteins, a post-translational conversion of arginine residues to citrulline, is recognized in rheumatoid arthritis, but largely undocumented in cancer. Here we show that citrullination of th...
-
Article
Open AccessClinical utility of RASSF1A methylation in human malignancies
The high frequency of RASSF1A methylation has been noted in a vast number of patients in a broad spectrum of malignancies, suggesting that RASSF1A inactivation is associated with cancer pathogenesis. However, whe...
-
Chapter and Conference Paper
HARNESS Project: Managing Heterogeneous Computing Resources for a Cloud Platform
Most cloud service offerings are based on homogeneous commodity resources, such as large numbers of inexpensive machines interconnected by off-the-shelf networking equipment and disk drives, to provide low-cos...
-
Article
Open AccessP03-09. Preserved adaptive immune responses and limited immune activation in CD4-low SIV-positive sooty mangabeys
-
Article
Delayed diagnosis in a sight-threatening lesion
Acute chiasmal compression has several aetiologies including pituitary apoplexy, a medical emergency caused by acute haemorrhagic or ischemic infarction in pituitary macroadenomas. Clinical diagnosis can often...
-
Chapter and Conference Paper
Design Tools for Pervasive Computing in Urban Environments
-
Article
Open AccessConferring specificity on the ubiquitous Raf/MEK signalling pathway
The Raf-MEK-ERK signalling pathway controls fundamental cellular processes including proliferation, differentiation and survival. It remains enigmatic how this pathway can reliably convert a myriad of extracel...
-
Article
Dehiscence of radial keratotomy incision during phacoemulsification
-
Article
Aqueous misdirection following needling of trabeculectomy bleb
-
Article
Anisotropic and inhomogeneous solutions of the Einstein-Boltzmann equations for Friedmann-Robertson-Walker spacetimes
It is shown how the techniques that yield anisotropic and inhomogeneous solutions of the Einstein-Liouville equations for Friedmann-Robertson-Walker (FRW) spacetimes can be used to demonstrate the existence of...