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  1. No Access

    Article

    A novel pathway producing dimethylsulphide in bacteria is widespread in soil environments

    The volatile compound dimethylsulphide (DMS) is important in climate regulation, the sulphur cycle and signalling to higher organisms. Microbial catabolism of the marine osmolyte dimethylsulphoniopropionate (D...

    O. Carrión, A. R. J. Curson, D. Kumaresan, Y. Fu, A. S. Lang… in Nature Communications (2015)

  2. No Access

    Article

    Genetic background determines the response to adenovirus-mediated wild-type p53 expression in pancreatic tumor cells

    The development of new therapies is particularly urgent with regard to pancreatic tumors. Gene therapy approaches involving p53 replacement are promising due to the central role of p53 in the cellular response...

    M Cascalló, E Mercadé, G Capellà, F Lluís, C Fillat, A M Gómez-Foix… in Cancer Gene Therapy (1999)

  3. No Access

    Article

    Enhanced pancreatic tumor regression by a combination of adenovirus and retrovirus-mediated delivery of the herpes simplex virus thymidine kinase gene

    We have evaluated the effectiveness of combining the different characteristics of retrovirus and adenovirus to apply the herpes simplex virus thymidine kinase gene (HSVtk) and ganciclovir (GCV) treatment for g...

    M Carrió, A Romagosa, E Mercadé, A Mazo, M Nadal, A-M Gómez-Foix, C Fillat in Gene Therapy (1999)

  4. No Access

    Article

    7,10-Dihydroxy-8(E)-octadecenoic acid produced by Pseudomonas 42A2: evaluation of different cultural parameters of the fermentation

    A fermentation process for the microbial production of a new lipid surface-active compound, 7,10-dihydroxy-8 (E)-octadecenoic acid (OCD), has been established using a vegetable oil as carbon source in a coordinat...

    C. De Andrés, E. Mercadé, J. Guinea… in World Journal of Microbiology and Biotechn… (1994)