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  1. Article

    Open Access

    The validation study on a three-dimensional burn estimation smart-phone application: accurate, free and fast?

    Accurate total body surface area burned (TBSAB) estimation is a crucial aspect of early burn management. It helps guide resuscitation and is essential in the calculation of fluid requirements. Conventional met...

    A. K. W. Cheah, T. Kangkorn, E. H. Tan, M. L. Loo, S. J. Chong in Burns & Trauma (2018)

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  2. No Access

    Article

    Multicenter phase II study of the AKT inhibitor MK-2206 in recurrent or metastatic nasopharyngeal carcinoma from patients in the mayo phase II consortium and the cancer therapeutics research group (MC1079)

    Background This study investigated the activity of MK-2206, an AKT inhibitor, in metastatic or recurrent nasopharyngeal carcinoma (NPC). Method Oral MK-2206 at a dose of 200 mg was admini...

    B. B. Y. Ma, B. C. Goh, W. T. Lim, E. P. Hui, E. H. Tan… in Investigational New Drugs (2015)

  3. No Access

    Article

    Functions of TAp63 and p53 in restraining the development of metastatic cancer

    Many tumours harbour mutations in the p53 tumour-suppressor gene that result in the expression of a mutant p53 protein. This mutant p53 protein has, in most cases, lost wild-type transcriptional activity and c...

    E H Tan, J P Morton, P Timpson, P Tucci, G Melino, E R Flores, O J Sansom… in Oncogene (2014)

  4. Article

    Open Access

    Graft-vs-tumor effect in patients with advanced nasopharyngeal cancer treated with nonmyeloablative allogeneic PBSC transplantation

    While nonmyeloablative peripheral blood stem cell transplantation (NST) has shown efficacy against several solid tumors, it is untested in nasopharyngeal cancer (NPC). In a phase II clinical trial, 21 patients...

    H C Toh, W K Chia, L Sun, C H Thng, Y Soe, Y P Phoon… in Bone Marrow Transplantation (2011)

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  5. No Access

    Article

    Control of emsis by intravenous granisetron in breast cancer patients treated with 5-FU, epirubicin and cyclophosphamide

    Granisetron, a potent and selective 5-hydroxytryptamine receptor (5-HT3) antagonist was reported to be an effective antiemetic agent both in animal studies and in patients given highly emetogenic chemotherapy. A ...

    E. -H. Tan, P. -T. Ang, K. -S. Khoo in Supportive Care in Cancer (1994)